Recruiting

Observational Study

Sponsor:

University of Washington

Code:

NCT06457841

Conditions

Alcohol Use

Cannabis Use

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Interventions

Direct Interpersonal Exchange

Vicarious Interpersonal Exchange

Daily Hassles

Study Details

Brief summary:

Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experiences may lead to alcohol and cannabis use. The proposed research is also designed to identify possible targets for prevention and treatment efforts to help reduce drug use.

Conditions

Alcohol Use

Cannabis Use

Study ID

NCT06457841

Start date

May 9, 2024

Status verified date

Jul, 2025

Completion date

Jul, 2027

Anticipated

Primary completion date

Jul, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Of Afro-descent
  • Proficient in English
  • Alcohol and/or cannabis use at least 2-3 times in the past month
  • Endorse having used alcohol and/or cannabis to cope

Exclusion Criteria:

  • Having participated in similar studies by the research team
  • Obtain cut-off scores on scale items indicating possible loss of control and needing to cut down or quit alcohol and/or cannabis use
  • In or seeking treatment for alcohol and/or cannabis use disorder

Study Design

Enrollment

456 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Direct Interpersonal Exchange

Simulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives

experimental: Vicarious Interpersonal Exchange

Hearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background

placebo comparator: Daily Hassles

Day-to-day stressors associated with school, work, finances

Interventions

Direct Interpersonal Exchange

Simulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives

Vicarious Interpersonal Exchange

Hearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background

Daily Hassles

Day-to-day stressors associated with school, work, finances

Primary outcome measure

  • Momentary Alcohol and/or Cannabis Craving [ Time Frame: Immediately after the intervention (i.e., within 1 minute) ]
  • Duration of Alcohol and Cannabis Intoxication [ Time Frame: 48 Hours Post-Intervention ]

Central Contacts and Locations

Central contacts

P. Priscilla Lui, Ph.D.

206-685-8391pplui@uw.edu

Locations

Southern Methodist University

Recruiting

Dallas, Texas, United States, 75204

Contacts

Ernest N Jouriles, Ph.D.

214-768-2360ejourile@smu.edu

University of Washington

Recruiting

Seattle, Washington, United States, 98195

Contacts

P. Priscilla Lui, Ph.D.

206-685-8391pplui@uw.edu

More Information

Sponsor

University of Washington

Last update posted

Jul 15, 2025

Last verified

Jul, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Washington on 2025-07-15.