Recruiting

Observational Study

Sponsor:

Oregon Health and Science University

Code:

NCT06461962

Conditions

Methamphetamine Use

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Treatment as Usual

Telehealth-Cardiology

Study Details

Brief summary:

The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology care for people who use methamphetamine in rural areas.

Conditions

Methamphetamine Use

Heart Failure

Study ID

NCT06461962

Start date

Aug 19, 2024

Status verified date

Mar, 2025

Completion date

Jun 30, 2029

Anticipated

Primary completion date

Jun 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patient-defined regular use of methamphetamine in the last year
  • Any methamphetamine use in the past 30 days
  • Age 18 years or older
  • No client-reported diagnosis of heart failure
  • Able to communicate in English
  • Screen positive for potential methamphetamine-associated heart failure (MAHF) defined as B type natriuretic peptide (BNP) ≥50 pg/ml, or QRS width ≥120ms, or presence of any clinical heart failure symptoms

Exclusion Criteria:

  • Self-reported engagement in medical care for heart failure in past 6 months.
  • Actively taking medications for heart failure.

Study Design

Enrollment

200 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Screening

Interventions and Outcome Measures

Arms

active comparator: Peer-supported Treatment as Usual

Participants will receive a peer-supported referral to a local primary care provider who will create a plan to treat the participants heart failure.

experimental: Peer-Supported Telehealth Cardiology

Participants will receive a virtual consultation with a cardiovascular specialist, referral for a locally performed echocardiogram (ECG), and transitional care management facilitated by a remote nurse care manager and the peer to treat the participants heart failure.

Interventions

Treatment as Usual

Peer-facilitated referral to a local primary care provider to follow-up their screening results.

Telehealth-Cardiology

Peer-facilitated virtual consultation with cardiovascular specialist, for follow-up of their screening results. Activities may include: referral for a locally performed testing including echocardiogram and additional blood work, and transitional care management facilitated by a remote nurse care manager and the peer

Referral for a locally performed testing including echocardiogram

Transitional care management facilitated by a remote nurse care manager and the peer

Primary outcome measure

  • Linkage to cardiology care [ Time Frame: 2 months ]

Central Contacts and Locations

Central contacts

Brian Chan, MD, MPH

503-494-2010chanbri@ohsu.edu

Kellie Pertl, MPH

pertl@ohsu.edu

Locations

Oregon Health & Science University

Recruiting

Portland, Oregon, United States, 97239

Contacts

Brian Chan, MD, MPH

503-494-2010chanbri@ohsu.edu

More Information

Sponsor

Oregon Health and Science University

Last update posted

Mar 21, 2025

Last verified

Mar, 2025

Keywords

  • Screening
  • Implementation Science
  • Heart Failure
  • Addiction
  • Stimulants
  • Health Services
  • Community Engaged Research

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Oregon Health and Science University on 2025-03-21.