Recruiting

Observational Study

Sponsor:

Louisiana State University and A&M College

Code:

NCT06466876

Conditions

Autism Spectrum Disorder

Eligibility Criteria

Sex: All

Age: 4 - 10

Healthy Volunteers: Not accepted

Interventions

retrieval-based word learning

Study Details

Brief summary:

Children on the autism spectrum sometimes have difficulty learning new words and using the newly taught information in different situations. In this study, the investigators are testing whether strategies that have been found to improve word learning in non-autistic children will also help autistic children. Specifically, the investigators aim to test whether autistic children learn words more successfully if novel words are taught by repeating the words to the child (re-study) or if the novel words are taught first with labeling each word and then quizzing the child (repeated quizzing).

The main questions it aims to answer are:

  • When teaching nouns (names of exotic animals), is learning stronger if autistic children re-study or engage in repeated quizzing of the newly taught words?
  • When teaching adjectives (visible features of objects, like a bumpy chair), is learning stronger if autistic children re-study or engage in repeated quizzing of the newly taught adjectives?
  • Does the word learning condition (re-study vs. repeated quizzing) impact whether autistic children are more successful in demonstrating their knowledge of the newly taught words in different contexts?
  • Are autistic features related to patterns of word learning?

Participants will:

  • Learn new words with half of the words being taught in one way (re-study) and the other half of the words being taught in the other way (repeated quizzing).
  • Participate in 5-minute and 1-week tests of the newly taught words to measure child learning.
  • Complete other language, thinking, and autism clinical assessments.

Conditions

Autism Spectrum Disorder

Study ID

NCT06466876

Start date

Jul 28, 2023

Status verified date

Jun, 2026

Completion date

Sep 30, 2026

Anticipated

Primary completion date

Sep 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 4 - 10

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Children with autism spectrum disorder (ASD) will participate in this study. The study will be 4- to 10-years-old and will already have a community diagnosis of autism spectrum disorder. The diagnosis will be confirmed confirmed using the Autism Diagnostic Observation Schedule - 2nd edition (ADOS-2; Lord et al., 2012).
  • Because the children will be completing an experimental word learning study that requires the child to verbally produce the newly taught words, children must have verbal communication skills (i.e., be able to speak in at least simple sentences spontaneously), which will be determined in initial correspondence with the child's parent or guardian.
  • Children's primary language spoken must be English.
  • All children will pass a hearing screening.
  • Additionally, all children will score above 75 on the Leiter-3 (Roid, Miller, \& Pomplun, 2013), a nonverbal cognitive assessment.

Exclusion Criteria:

  • Because the word learning study involves the child needing to produce the taught words non-speaking autistic children and minimally speaking autistic children (i.e., is not able to produce at least simple sentences in spontaneous speech) will be excluded from the proposed studies.
  • If the child has a history of a neurological disorder such as cerebral palsy or a known genetic disorder that causes developmental delays/disorders
  • If the child has an un-corrected hearing loss.

Study Design

Enrollment

64 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Word Learning

Each autistic child will be taught novel words in a behavioral task.

Interventions

retrieval-based word learning

Word learning intervention that compares two strategies for teaching novel words

Primary outcome measure

  • Word form recall [ Time Frame: During the 5-minute test and 1-week test (for taught and generalization referents) for Studies 1 and 2 ]
  • Word meaning recall [ Time Frame: During the 5-minute test and 1-week test (for taught and generalization referents) for Studies 1 and 2 ]
  • Form-referent-link recognition [ Time Frame: During the 1-week test (for taught and generalization referents) for Studies 1 and 2 ]

Central Contacts and Locations

Central contacts

Eileen K Haebig, PhD

225-578-3933ehaebig1@lsu.edu

Christopher R Cox, PhD

225-578-8745chriscox@lsu.edu

Locations

Louisiana State University

Recruiting

Baton Rouge, Louisiana, United States, 70803

Contacts

Eileen K Haebig, PhD

225-578-3933ehaebig1@lsu.edu

Christopher R Cox, PhD

225-578-8745chriscox@lsu.edu

More Information

Sponsor

Louisiana State University and A&M College

Last update posted

Jun 8, 2026

Last verified

Jun, 2026

Keywords

  • autism
  • word learning
  • retrieval practice
  • test effect

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Louisiana State University and A&M College on 2026-06-08.