Recruiting

Golf

Sponsor:

University of Southern California

Code:

NCT06500169

Conditions

Localized Prostate Carcinoma

Locally Advanced Prostate Carcinoma

Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

Stage II Prostate Cancer AJCC v8

Stage III Prostate Cancer AJCC v8

Eligibility Criteria

Sex: Male

Age: 55 - 70+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Discussion

Exercise Intervention

Interview

Medical Device Usage and Evaluation

Study Details

Brief summary:

This clinical trial evaluates a golf recreational exercise program for enhancing survivorship in underrepresented prostate cancer survivors. Golf is a multimodal recreational activity that requires participants to utilize all muscle groups to perform the golf swing, walk over hilly and uneven terrain, maintain balance during putting and squat-like tasks. Physical activity and exercise are beneficial to physical function, cognitive function, psychosocial health, and overall quality of life during prostate cancer survivorship. These aspects of health are impacted by prostate cancer treatment, especially androgen deprivation therapy. Additionally, supervised, group-based activity programs facilitate participation in physical activity. Researchers want to examine the changes in functional abilities, psychosocial health, and quality of life following participation in in a golf program designed for prostate cancer survivors.

Conditions

Localized Prostate Carcinoma

Locally Advanced Prostate Carcinoma

Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8

Stage II Prostate Cancer AJCC v8

Stage III Prostate Cancer AJCC v8

Study ID

NCT06500169

Start date

Sep 1, 2023

Status verified date

May, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 55 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • First time, primary diagnosis of prostate cancer (PCa)
  • Currently receiving androgen deprivation therapy (ADT) and/or androgen receptor blocker) for more than 6 months
  • Older adult male: 55-85 years old
  • The ability to stand independently without external support
  • No or minimal golf experience (played < 5 times in the past 10 years)
  • English speaking

Exclusion Criteria:

  • Second cancer diagnosis (excluding non-invasive skin cancers) or bone metastases
  • Prostatectomy less than 6 months prior to study enrollment (prostatectomy is not a requirement for study entry)
  • Symptomatic cardiovascular disease, active angina, uncontrolled hypertension (systolic blood pressure (SBP) > 160 or diastolic blood pressure (DBP) > 90, high resting pulse heart rate (HR) > 90), symptomatic orthostatic hypotension
  • Unstable asthma, exacerbated chronic obstructive pulmonary disease (COPD\]
  • History of injury or orthopedic operation within the last 6 months
  • Movement disorders (e.g., Parkinson's disease (PD) or other neurological disorders), hemiparesis or paraparesis
  • Severe vision or hearing problems

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Supportive care (golf program)

Patients participate in the golf training program composed of group sessions over 1-2 hours with a PGA professional two times per week for ten weeks. Training consists of complimentary/warm up exercises integrated with pelvic floor muscle training, golf instruction, golf practice, and golf play on a Par 3 public golf course. Patients also wear an activity tracker and undergo blood sample collection on the study.

Interventions

Biospecimen Collection

Undergo blood sample collection

Discussion

Ancillary studies

Exercise Intervention

Complete golf related exercises

Interview

Ancillary studies

Medical Device Usage and Evaluation

Wear activity tracker

Physical Examination

Ancillary studies

Physical Performance Testing

Ancillary studies

Questionnaire Administration

Ancillary studies

Recreational Therapy

Participate in golf program

Primary outcome measure

  • Enrollment rate [ Time Frame: Up to 3 years ]
  • Participant adherence to the program [ Time Frame: Up to 3 years ]
  • Cost of the program [ Time Frame: Up to 3 years ]
  • Staff adherence [ Time Frame: Up to 3 years ]
  • Program accommodations [ Time Frame: Up to 3 years ]
  • Incidence of adverse events [ Time Frame: Up to 3 years ]
  • Quality of life scores [ Time Frame: Up to 3 years ]
  • Circulating inflammatory biomarker levels [ Time Frame: Up to 3 years ]
  • Senior fitness test scores [ Time Frame: Up to 3 years ]
  • Gait speed [ Time Frame: Up to 3 years ]
  • Balance Confidence [ Time Frame: Up to 3 years ]
  • Cognitive function [ Time Frame: Up to 3 years ]
  • Participant feedback of the program [ Time Frame: Up to 3 years ]

Central Contacts and Locations

Central contacts

Garry Cai

(323)442-3113Guanrong@usc.edu

Locations

Los Angeles General Medical Center

Recruiting

Los Angeles, California, United States, 90033

Contacts

George Salem, PhD

323-442-3113gsalem@usc.edu

Principal Investigator:

George Salem, PhD

USC / Norris Comprehensive Cancer Center

Recruiting

Los Angeles, California, United States, 90033

Contacts

George Salem, PhD

323-442-3113gsalem@usc.edu

Principal Investigator:

George Salem, PhD

More Information

Sponsor

University of Southern California

Last update posted

Jun 3, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Southern California on 2026-06-03.