Recruiting

Eccentric Exercise

Sponsor:

Hunter College of City University of New York

Code:

NCT06505421

Conditions

Multiple Sclerosis

Fatigue

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Resistance training

Study Details

Brief summary:

The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.

Conditions

Multiple Sclerosis

Fatigue

Study ID

NCT06505421

Start date

Jul 1, 2024

Status verified date

Jul, 2024

Completion date

Dec 30, 2026

Anticipated

Primary completion date

Dec 30, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Definitive diagnosis of Multiple Sclerosis.
  • Ability to walk for 6 minutes continuously with or without assistive device
  • Ability read, understand and sign and informed consent

Exclusion Criteria:

  • Evidence of recent exacerbation in the last 2 months prior to starting the study
  • Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol

Study Design

Enrollment

30 participants

Anticipated

Interventions and Outcome Measures

Arms

Persons with Multiple sclerosis

Eccentric resistance training , traditional resistance training

Interventions

Resistance training

Eccentric resistance training and tradional resistance training

Primary outcome measure

  • 6-Minute walk test [ Time Frame: Pre-intervention and post intervention for each condition (eccentric and traditional strength training). There is a 36-48 hour period between the pre-intervention and post intervention for each condition ]

Central Contacts and Locations

Central contacts

Locations

Hunter College, Physical Therapy Department, City University of New York

Recruiting

New York, New York, United States, 10010

Contacts

More Information

Sponsor

Hunter College of City University of New York

Last update posted

Jul 17, 2024

Last verified

Jul, 2024

Keywords

  • Exercise
  • resistance training

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Hunter College of City University of New York on 2024-07-17.