Recruiting
Early Phase 1

Observational Study

Sponsor:

University of Texas at Austin

Code:

NCT06511752

Conditions

Alzheimer Disease

Dementia

Primary Progressive Aphasia

Aphasia

Progressive Aphasia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Psychosocial educational, support group and implementation of strategies

Study Details

Brief summary:

The current study aims to examine the benefits of an education/support group program for individuals with progressive aphasia (caused by various etiologies, diagnoses) and their carepartners. The current study utilizes pre-, post-treatment, and follow-up assessments to measure effects of a psychoeducational support group and an implementation/communication skills training phase on measures of psychosocial function, communicative effectiveness and speech/language function. Analysis of study-specific surveys and semi-structured interviews will provide qualitative data regarding outcomes. Before beginning the education and support group, focus groups will be run in order to set priorities for the themes to be included in the education program. Participants will join via tele-based means if preferred and these participants may reside in the United States, or internationally including Mexico and Spain.

Conditions

Alzheimer Disease

Dementia

Primary Progressive Aphasia

Aphasia

Progressive Aphasia

Study ID

NCT06511752

Start date

May 21, 2024

Status verified date

Jun, 2026

Completion date

Dec, 2030

Anticipated

Primary completion date

May, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

All participants must:

  • speak Spanish and/or English (although participants may speak other languages in addition to Spanish and/or English)
  • identify as Hispanic and/or Latinx,
  • or their spouse/family member with PA identifies as Hispanic and/or Latinx
  • see and hear well enough to participate
  • have access to a computer or mobile device with video capability
  • have an internet connection

Additional inclusion criteria for PA/ language-led dementia support group participants:

  • Individuals with PA:
  • Has a diagnosis of PA, or language-led dementia, and aphasia is one of the primary causes of difficulty with activities of daily living
  • Aware of language difficulties and willing to discuss them
  • Able to actively engage in group discussion and complete activities with minimal support
  • Able to regularly attend meetings
  • Willing to follow the rules of the support group for interacting with others respectfully

Additional inclusion criteria for care partner support group plus implementation phase participants:

  • Individuals with PA:
  • Diagnosis of aphasia or dementia that is progressive in nature, and aphasia is one of the primary causes of difficulty with activities of daily living
  • Have some ability to communicate and understand communication in order to participate in training sessions
  • Are functionally able to engage in training sessions (e.g., able to maintain some attention, minimal challenging behavior that would cause disruption)
  • Have a care partner who also consents to participating in the project
  • Care partners:
  • Self-identification as a caregiver of an individual with a diagnosis of PA or language-led dementia
  • Willing to discuss caregiving for individuals with PA/ language-led dementia
  • Able to regularly attend meetings
  • Willing to follow the rules of the support group for interacting with others respectfully

Exclusion Criteria:

• Beyond the inclusion criteria included above, no additional exclusion criteria apply

Study Design

Enrollment

120 participants

Anticipated

Allocation

Non randomized

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Treatment Condition

Support group meetings and strategy practice

Interventions

Psychosocial educational, support group and implementation of strategies

Psychosocial educational, support group and implementation of strategies

Primary outcome measure

  • Treatment/Acceptability Survey [ Time Frame: Baseline, Immediately following treatment, Follow-up at 3-months post-treatment ]

Central Contacts and Locations

Central contacts

Stephanie M Grasso, PhD

6268648957smgrasso@austin.utexas.edu

Locations

University of Texas at Austin

Recruiting

Austin, Texas, United States, 78702

Contacts

Diana F Cruz

(512) 471-3420diana.cruz@austin.utexas.edu

More Information

Sponsor

University of Texas at Austin

Last update posted

Jun 10, 2026

Last verified

Jun, 2026

Keywords

  • bilingual
  • Spanish
  • Castellano
  • multicultural
  • multilingual

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Texas at Austin on 2026-06-10.