Recruiting

Acupuncture

Sponsor:

University of Chicago

Code:

NCT06516198

Conditions

Frailty

Thoracic

Prehabilitation

Lung Surgery

Wedge Resection

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

Auricular Acupressure

Study Details

Brief summary:

Complementary medicine is recognized for its ability to enhance appetite, increase energy, reduce anxiety, decrease pain, and improve sleep, among many other benefits. Acupuncture is among the most frequent types of complementary medicine practiced in the US, and Medicare currently includes back pain as a reimbursable indication for this therapy. Acupuncture-related therapies may enhance efforts at prehabilitation in candidates for major lung resection.

Conditions

Frailty

Thoracic

Prehabilitation

Lung Surgery

Wedge Resection

Study ID

NCT06516198

Start date

Jul 21, 2025

Status verified date

Nov, 2025

Completion date

Jun 20, 2027

Anticipated

Primary completion date

Jun 20, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Inclusion Criteria

  • Being considered for major lung surgery
  • Surgery is not scheduled for at least 2 weeks
  • Age ≥ 50 years
  • Able to understand English at a 4th grade level
  • No known contraindications to prehabilitation (strength, endurance, balance exercises)
  • Able to provide informed consent for participation
  • Has an adult care partner who will be available and capable of placing seeds
  • Has access to smart phone for communication and image sharing
  • Underwent frailty screening (given any score)
  • Able to perform spirometry testing in clinic

Exclusion Criteria:

  • Allergy to Vaccaria seeds
  • Medical condition affecting either ear preventing use of auricular acupressure such as eczema, frostbite, sunburn

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Experimental Group

A random number card will be drawn in sequence from a box. Even numbered cards will assign the patient to the experimental group, odd numbered cards will assign the patient to the control group.

o Intervention group seed points:

1. Shen Men (anxiety, depression, stress, pain)
2. Point 0 (homeostasis, energy, mood)
3. Endocrine (hormonal homeostasis)
4. Subcortex (insomnia, anxiety, pain, inflammation)
5. Autonomic (autonomic balance, pain)

sham comparator: Control Group

A random number card will be drawn in sequence from a box. Even numbered cards will assign the patient to the experimental group, odd numbered cards will assign the patient to the control group.

o Control group sham seed points:

1. Inside edge, center of tragus
2. Helix midway between apex and tubercle
3. Helix 1 cm anterior to apex
4. 5 mm anterior to Shen Men
5. Covered, 5 mm anterior and superior to endocrine

For the sham intervention (Sham Type II, same intervention with seeding and intermittent pressing) the seeds are placed at nonacupressure points for the control group.

Interventions

Auricular Acupressure

Seeds will be placed during the clinic visit by the acupuncturist or the research associate according to the group the patient was assigned to. The care partner will observe the placement. A photograph of the seed placement will be taken and given to the care partner and to the patient after the relevant points are labeled by number or letter. The method of pressing is demonstrated for 1 one of the seeds, the care partner practices pressing on 2 other seeds, and the patient practices pressing on the remaining 2 seeds. Pressing consists of applying pressure, gradually increasing the pressure until the patient expresses discomfort, and maintaining that pressure until 2 minutes have passed. After pressing has been performed for each seed, the seeds are removed in clinic prior to clinic discharge.

Primary outcome measure

  • Number of patients enrolled [ Time Frame: 2 weeks ]

Central Contacts and Locations

Central contacts

Locations

University of Chicago

Recruiting

Chicago, Illinois, United States, 60637

Contacts

More Information

Sponsor

University of Chicago

Last update posted

Dec 9, 2025

Last verified

Nov, 2025

Keywords

  • accupressure
  • vaccaria seeds

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Chicago on 2025-12-09.