Recruiting

Venous Assessment & Compression

Sponsor:

Mayo Clinic

Code:

NCT06519435

Conditions

Deep Vein Thrombosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Mayo Dopplex ABIlity

Intermittent Pneumatic Compression (IPC)

Study Details

Brief summary:

The purpose of this research is to measure changes in venous blood flow with an air-filled bladder under an intermittent pneumatic compression device cuff (used to prevent deep venous thrombosis) or venous diagnostic device cuff (used to detect deep venous thrombosis). The devices being used in the study are investigational and not FDA-cleared.

Conditions

Deep Vein Thrombosis

Study ID

NCT06519435

Start date

Nov 15, 2024

Status verified date

Oct, 2025

Completion date

Apr, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Venous ultrasound study to evaluate for lower extremity DVT unilateral and/or bilateral within previous 72 hours.

Exclusion Criteria:

  • Patients with inaccessible target limb (ultrasound limb) due to bandages (wound, burn, lesion, etc) or cast.
  • Patients with leg trauma, fracture, above or below knee amputation, or other condition in which compressing on the calf is medically inappropriate or not possible.
  • Patients unable to provide informed written consent.

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Interventions

Mayo Dopplex ABIlity

Device used to measure lower extremity venous hemodynamic pressure

Intermittent Pneumatic Compression (IPC)

Device used to measure lower extremity venous hemodynamic pressure

Primary outcome measure

  • Mayo Dopplex ABllity device Venous hemodynamic pressure [ Time Frame: Baseline ]
  • Intermittent Pneumatic Compression device Venous hemodynamic pressure [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

David Liedl

507-266-6717liedl.david@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

David Liedl

800-664-4542liedl.david@mayo.edu

Gonda Vascular Center

507-266-6717

More Information

Sponsor

Mayo Clinic

Last update posted

Oct 28, 2025

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2025-10-28.