Recruiting

AVOID & RESIST

Sponsor:

Cedars-Sinai Medical Center

Code:

NCT06521021

Conditions

Overweight and Obesity

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

AVOID

RESIST

Study Details

Brief summary:

This trials will formally test whether participants' active choice of self-regulatory strategies (AVOID or RESIST) leads to greater adherence to weight management strategies by comparing the CHOICE arms to the randomized arms of the parent intervention, AVOID/RESIST (IRB STUDY00001652: AVOID-RESIST).

Conditions

Overweight and Obesity

Study ID

NCT06521021

Start date

Jun 1, 2026

Status verified date

Feb, 2026

Completion date

Jul 1, 2027

Anticipated

Primary completion date

Jul 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age 18 years or older
  • BMI between 25-45 kg/m2
  • Read, write, and speak English with acceptable visual acuity

Exclusion Criteria:

  • Currently enrolled in weight loss interventions or undergoing bariatric surgery
  • Pregnant women
  • Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse)
  • Individuals who have pacemakers or other electronic medical device implantations
  • Individuals with severe cognitive delays or visual/hearing impairment
  • Individuals who are unable or unwilling to complete the study assessments / measurements
  • Individuals currently subscribed to a meal delivery service who are unwilling to pause their subscription for the duration of the study

Study Design

Enrollment

60 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

other: WW + Home modification and grocery delivery (AVOID)

WW + modification of home food environment + online grocery shopping and delivery

Arm assignment is selected by participant.

other: WW + Inhibitory control training (RESIST)

WW + daily gamified inhibitory control training

Arm assignment is selected by participant.

Interventions

AVOID

Behavioral: Home food environment and grocery delivery (AVOID) Participants will receive coaching (Zoom and/or email/text) to modify their home food environment and alter cues to promote healthy food choices

Behavioral: WW Participants assigned to all arms will receive of coaching (Zoom and/or email/text) and commercially-available weight management program focusing on diet, physical activity and mindset skills.

RESIST

Behavioral: Inhibitory control training (RESIST) Participants assigned to RESIST will receive coaching (Zoom and/or email/text) and gamified inhibitory control training.

Behavioral: WW Participants assigned to all arms will receive coaching (Zoom and/or email/text) and commercially-available weight management program focusing on diet, physical activity and mindset skills.

Primary outcome measure

  • Completion Rate of Follow-up Visits [ Time Frame: 3 Month, 6 Month ]

Central Contacts and Locations

Central contacts

Julissa Ruiz, BS

(310) 602-4169julissa.ruiz@cshs.org

Sarah-Jeanne Salvy, PhD

sarah.salvy@cshs.org

Locations

Cedars-Sinai Medical Center

Recruiting

Beverly Hills, California, United States, 90211

Contacts

Julissa Ruiz, BS

julissa.ruiz@cshs.org

Sarah-Jeanne Salvy, PhD

sarah.salvy@cshs.org

Principal Investigator:

Sarah-Jeanne Salvy, PhD

More Information

Sponsor

Cedars-Sinai Medical Center

Last update posted

Sep 22, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-24. This information was provided to ClinicalTrials.gov by Cedars-Sinai Medical Center on 2026-09-22. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.