Recruiting

Observational Study

Sponsor:

Denver Health and Hospital Authority

Code:

NCT06532734

Conditions

Barrett Esophagus

Anorexia Nervosa, Binge Eating/Purging Type

Rumination

Vomiting

Eating Disorders

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

EsoGuard

Study Details

Brief summary:

To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors

Conditions

Barrett Esophagus

Anorexia Nervosa, Binge Eating/Purging Type

Rumination

Vomiting

Eating Disorders

Study ID

NCT06532734

Start date

Nov 12, 2024

Status verified date

Dec, 2025

Completion date

Nov, 2026

Anticipated

Primary completion date

Nov, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients diagnosed with an eating disorder diagnosis that includes purging history
  • Ages 18-65
  • Purging history =>5 years
  • Purging or rumination at a minimum of once daily upon admission.
  • Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition

Exclusion Criteria:

  • Any eating disorder diagnosis that does not include purging behaviors
  • Ages under 18 and over 65
  • Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background)
  • Received mandated care at time of enrollment
  • Inability to consent to participate in the research

Study Design

Enrollment

25 participants

Anticipated

Interventions and Outcome Measures

Arms

AN-BP

individuals with a dx of AN-BP, with a >5-year history of purging, with a frequency of at least once a day.

Interventions

EsoGuard

device used to collect esophageal cell samples to test for the presence of abnormal cells which may indicate a dx of Barrett's esophagitis.

Primary outcome measure

  • Number of patients positive for BE [ Time Frame: 12 months ]

Central Contacts and Locations

Central contacts

Marina J Foster, BA

303-602-1913marina.foster@dhha.org

Allison Nitsch, MD

303-602-5067Allison.nitsch@dhha.org

Locations

ACUTE Center for Eating Disorders and Severe Malnutrition

Recruiting

Denver, Colorado, United States, 80204

Contacts

Marina J Foster, BA

303-602-1913marina.foster@dhha.org

Alllison Nitsch, MD

303-602-5067dennis.gibson@dhha.org

Denver Health and Hospital Authority

Recruiting

Denver, Colorado, United States, 80204

Contacts

Marina Foster

3036021913marina.foster@dhha.org

Denver Health and Hospital Authority

Recruiting

Denver, Colorado, United States, 80204

Contacts

Marina J Foster, BA

303-602-1913marina.foster@dhha.org

Alllison Nitsch, MD

303-602-7701Allison.nitsch@dhha.org

Principal Investigator:

Allison Nitsch, MD

More Information

Sponsor

Denver Health and Hospital Authority

Last update posted

Dec 10, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Denver Health and Hospital Authority on 2025-12-10.