Recruiting

mHealth Screening

Sponsor:

Memorial Sloan Kettering Cancer Center

Code:

NCT06535867

Conditions

Smoking

Smoking, Cigarette

Smoking, Tobacco

Betel Chewer's Mucosa

Tobacco Use

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

mHealth

Study Details

Brief summary:

Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers. This program is inclusive of long term surveillance to downstage oral cancer in India

Conditions

Smoking

Smoking, Cigarette

Smoking, Tobacco

Betel Chewer's Mucosa

Tobacco Use

Study ID

NCT06535867

Start date

Jul 30, 2024

Status verified date

May, 2026

Completion date

Jul 30, 2031

Anticipated

Primary completion date

Jul 30, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

Positive for any one or more of the following:

  • All individuals aged above 18 years positive for habits (smoking and smokeless tobacco, chewing betel leaf, areca nut, paan masala, and/or regular use of alcohol)
  • Clinical signs/symptoms (non-healing ulcers, white/ red/red \& white patches in the mouth, restriction of mouth opening and swelling of the neck)
  • All individuals aged above 40 irrespective of habit/oral lesions

Exclusion Criteria:

  • Individuals already diagnosed with oral cancer and undergoing treatment for oral cancer
  • Under treatment for tuberculosis or suffering from any acute illness/ debilitating systemic disorders

Study Design

Enrollment

5122 participants

Anticipated

Interventions and Outcome Measures

Arms

Participants from Varanasi

Participants will be recruited from Varanasi.

Interventions

mHealth

The mobile health (mHealth) program will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.

Primary outcome measure

  • Comparison of mHealth with conventional oral cancer screening [ Time Frame: Up to 5 years ]

Central Contacts and Locations

Central contacts

Milind Rajadhyaksha, PhD

646-608-2364rajadhym@mskcc.org

Aditi Sahu

646-608-1935sahua@mskcc.org

Locations

Memorial Sloan Kettering Cancer Center (All protocol activites)

Recruiting

New York, New York, United States, 10065

Contacts

Milind Rajadhyaksha, PhD

646-608-2364

More Information

Sponsor

Memorial Sloan Kettering Cancer Center

Last update posted

May 22, 2026

Last verified

May, 2026

Keywords

  • smoking
  • smoking, cigarette
  • smoking, tobacco
  • smokeless tobacco
  • betel leaf
  • areca nut
  • paan masala
  • alcohol use
  • Memorial Sloan Kettering Cancer Center
  • 24-148

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Memorial Sloan Kettering Cancer Center on 2026-05-22.