Recruiting

Digital Health Solutions

Sponsor:

University of Calgary

Code:

NCT06537453

Conditions

Acute Kidney Injury

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Virtual Care

Study Details

Brief summary:

Method: Randomized Controlled Trial Study Duration: 3 Years Study Centre(s) University of Calgary and University of Alberta Objectives: To fill care gaps by implementing strategies to reduce length of hospital stay, readmission rates, and improve long-term outcomes after Acute Kidney Injury (AKI). Number of Participants: Three Hundred and fifty four (n=354) Diagnosis and Main Inclusion Criteria: Hospitalized adults with AKI at high risk of hospital readmission or death

Study Intervention: Multi-component Digital Health Solutions, including:

1. Computerized Clinical Decision Support (CDS) and
2. Virtual Care Delivered through Hospital at Home (VC) Duration of administration: Determined by the Patient's clinical team Reference therapy: Usual Care Statistical Analyses: Descriptive Analysis, Regression

Conditions

Acute Kidney Injury

Study ID

NCT06537453

Start date

Aug 10, 2024

Status verified date

Apr, 2026

Completion date

Oct 31, 2026

Anticipated

Primary completion date

Aug 10, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18 years old.
  • AKI identified in hospital using Kidney Disease Improving Global Outcomes (KDIGO) criteria17.
  • Hospitalization > 48 hours.
  • LACE (L= Length patient Stay in the hospital, A= Acuity of Admission of patient in the hospital, C= Comorbidity and E= Emergency Visit.) Score 12 or higher.
  • Meets all inclusion criteria of Virtual Home Hospital programs of Calgary and Edmonton zones.

Exclusion Criteria:

  • Non-Alberta residents.
  • Resides outside the catchment areas for the Calgary and Edmonton Virtual Home Hospital programs.
  • C1 or C2 goals of care.
  • Hospitalization > 30 days.
  • Will be discharged to long-term care.
  • Kidney failure receiving dialysis.
  • Already admitted in Virtual Home Hospital Program

Study Design

Enrollment

354 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Virtual Care

Participants will receive virtual care through Virtual Home Hospital programs in Alberta for their hospital to home transition of care.

no intervention: Usual Care

Participants will be discharged as per usual care practices from hospital to their home.

Interventions

Virtual Care

Participants will go through Virtual hospital programs following the processes established by these programs in Alberta.

Primary outcome measure

  • the number of days alive out of hospital [ Time Frame: Up to 45 days from the date of randomization ]

Central Contacts and Locations

Central contacts

Director

+1 (403) 210. 6730cccr@ucalgary.ca

Locations

University of Calgary

Recruiting

Calgary, Alberta, Canada, T2N 1N4

Contacts

Nusrat Shommu, PhD

4032103991nsshommu@ucalgary.ca

Principal Investigator:

Matthew T James, MD PhD FRCPC

University of Alberta

Recruiting

Edmonton, Alberta, Canada, T6G 2G3

Contacts

Eila Mirhadi, MSc

mirhadi@ualberta.ca

Principal Investigator:

Neesh Pannu, MD SM FRCPC

More Information

Sponsor

University of Calgary

Last update posted

May 14, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Calgary on 2026-05-14.