Recruiting

Polyphenol-Rich Pulses

Sponsor:

University of Florida

Code:

NCT06538415

Conditions

Healthy

Eligibility Criteria

Sex: Female

Age: 45 - 65

Healthy Volunteers: Accepted

Interventions

Pulse Diet

Control Rice Diet

Study Details

Brief summary:

Skin health is influenced by the microbiome, lipids, oxidative stress, inflammation, and UV exposure. A 12-week trial with 48 women aged 45-65 will test if polyphenol-rich pulses improve skin health by affecting these factors. Using a white rice control diet, the study will measure skin parameters and analyze correlations with changes in lipids and microbiome, potentially proving the benefits of pulses.

Conditions

Healthy

Study ID

NCT06538415

Start date

May 12, 2026

Status verified date

Jul, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 45 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

  • BMI (18.5-29.9)
  • Body weight ≥110 pounds
  • Fitzpatrick skin type 1,2 and 3.

Exclusion Criteria:

  • pregnancy
  • breast-feeding
  • impaired fasting glucose
  • frequent alcohol use
  • history of skin cancer
  • sunbathing and the use of tanning bed, intake of vitamin/mineral supplements
  • habitual high intake of fruits (≥ 2 cups daily)
  • intake of medication that might influence the outcome of the study

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Pulse Diet

Participants will consume cooked pulses on an alternating basis over the 10-week intervention period. The pulses consist of 455 grams of the tri-bean blend (kidney, pinto, black bean), equivalent to 350 calories, and 225 grams of black lentils (400 calories).

active comparator: Control Rice Diet

Participants will consume cooked white rice (375 calories) over 10 weeks

Interventions

Pulse Diet

Participants will consume cooked pulses on an alternating basis over the 10-week intervention period. The pulses consist of 455 grams of the tri-bean blend (kidney, pinto, black bean), equivalent to 350 calories, and 225 grams of black lentils (400 calories).

Control Rice Diet

Participants will consume cooked white rice (375 calories) over 10 weeks

Primary outcome measure

  • Skin sensitivity after UV radiation [ Time Frame: 84 days ]

Central Contacts and Locations

Central contacts

Liwei Gu, PhD

(352)2943730lgu@ufl.edu

Ahmad Moussa, MS

(352) 392-0584moussaahmad@ufl.edu

Locations

Food Science and Human Nutrition

Recruiting

Gainesville, Florida, United States, 32608

Contacts

Liwei Gu, phd

352-294-3730lgu@ufl.edu

More Information

Sponsor

University of Florida

Last update posted

Jul 2, 2026

Last verified

Jul, 2026

Keywords

  • Pulse
  • Women
  • Skin health

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Florida on 2026-07-02.