Recruiting

CYT

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06545604

Conditions

Ovarian Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Yoga Therapy for Nutritional, Physical, and Psychosocial Prehabilitation

Usual care supportive services including nutrition counseling per usual care

Study Details

Brief summary:

To provide a comprehensive yoga therapy (CYT) program to patients with ovarian, fallopian tube, or primary peritoneal cancer who are scheduled to receive chemotherapy and then undergo surgery. Researchers want to learn about the effects of the program on patients' quality of life and other outcomes described below.

Conditions

Ovarian Cancer

Study ID

NCT06545604

Start date

Jun 6, 2025

Status verified date

Jul, 2026

Completion date

Jun 30, 2027

Anticipated

Primary completion date

Jun 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Women with stage III-IV epithelial ovarian, fallopian tube, primary peritonal cancer with recommendations for NACT/IDS at recruitment.
2. Able to read, write, and speak English.
3. 18 years of age or older.
4. Oriented to person, place, and time.
5. Access to internet connection.
6. Access to a tablet, laptop or computer or smart phone.
7. Access and ability to do virtual sessions.

9\. Plan for surgical intervention at MD Anderson Cancer Center 9. Performance status 0-2.

Exclusion Criteria:

1. Have completed chemotherapy.
2. Any major thought disorder (e.g., schizophrenia, dementia).
3. Any major communication barriers that would preclude being able to complete the intervention (e.g., visually or hearing impaired).
4. Extreme mobility issues (e.g., unable to get in and out of a chair unassisted).
5. Have a regular mind-body practice or an established yoga practice.

Study Design

Enrollment

55 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: CYT - Prehab Yoga Intervention + ERAS

experimental: WLC - Wait List Control + ERAS

Interventions

Yoga Therapy for Nutritional, Physical, and Psychosocial Prehabilitation

Two visits per week with a yoga therapist while receiving neoadjuvant chemotherapy to cover dietary counseling, yoga-based movement practices, breathwork practices, mind practices, and behavioral support for the purpose of preparing patients' mind and body for a planned surgery.

Usual care supportive services including nutrition counseling per usual care

Usual care supportive services while receiving neoadjuvant chemotherapy.

Primary outcome measure

  • To assess the feasibility of a CYT prehabilitation program in women with ovarian cancer scheduled to receive NACT and IDS. [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts and Locations

Central contacts

Lois Ramondetta, MD

(713) 745-0307lramonde@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Lois Ramondetta, MD

713-745-0307lramonde@mdanderson.org

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jul 29, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-07-29.