Recruiting

STRW-T

Sponsor:

Children's Hospital Medical Center, Cincinnati

Code:

NCT06552286

Conditions

Autism Spectrum Disorder

Eligibility Criteria

Sex: All

Age: 15 - 21

Healthy Volunteers: Not accepted

Interventions

STRW-T

PEERS-T

Study Details

Brief summary:

The current study seeks to compare outcomes of a telehealth intervention targeting daily living skills (Surviving and Thriving in the Real World - Telehealth, or STRW-T) intervention to a control group telehealth intervention targeting social skills (Program for the Education and Enrichment of Relational Skills- Telehealth, or PEERS-T). The key endpoint will be change in daily living skills on primary and secondary outcome measures at the end of treatment.

Conditions

Autism Spectrum Disorder

Study ID

NCT06552286

Start date

Jul 10, 2024

Status verified date

Mar, 2026

Completion date

Dec 31, 2029

Anticipated

Primary completion date

Dec 31, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 15 - 21

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • in the last 2 years of high school, or deferring graduation
  • diagnosis of ASD based on clinical judgement and/or meeting the cut-off score on the Autism Diagnostic Observation Schedule, 2nd Edition
  • full scale IQ of 70 or above as measured by the Wechsler Abbreviated Scale of Intelligence, 2nd Edition
  • deficient Daily Living Skills as assessed by the Vineland Adaptive Behavior Scales, 3rd Edition - at least 1 of the 3 Daily Living Skills subdomains is at least 15 points below their full scale IQ

Exclusion Criteria:

  • significant aggressive behaviors or mental health issues that require treatment out of the scope of the current intervention.
  • if the adolescent has already completed the social skills group (PEERS), either at Cincinnati Children's or in another setting, unless it has been a significant amount of time since they did the PEERS group (2-3 years, or up to the discretion of the PI).

Study Design

Enrollment

192 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Surviving and Thriving in the Real World - Telehealth (STRW-T)

randomized to STRW-T intervention

active comparator: Program for the Education and Enrichment of Relational Skills - Telehealth (PEERS-T)

randomized to PEERS-T intervention

Interventions

STRW-T

The STRW-T intervention consists of 15 weekly caregiver group sessions and caregiver-teen dyad sessions delivered via Zoom. The targeted daily living skills (DLS) have been identified and refined through our prior studies and include: Morning routine, laundry, kitchen/cooking, grocery shopping, and money management. Evidence-based strategies are utilized to facilitate acquisition, mastery, and generalization of specific DLS at home and in the community. During dyad sessions, teens will work on DLS in their home environment and will receive coaching and instruction from both their caregiver and the therapist. During caregiver group sessions, the therapist will discuss the content of dyad sessions and engage in problem solving with each caregiver (e.g., using and fading rewards, implementing strategies to increase success, teen motivation/buy-in).

PEERS-T

PEERS-T is a 15-week intervention with concurrent caregiver and teen group telehealth sessions that target social skills (e.g., building friendships, conversing, dealing with bullying). PEERS-T was chosen as the control because it is one of the few evidence-based interventions for autistic adolescents and does not address daily living skills. PEERS-T is also matched to STRW-T on duration and is clinically meaningful to families.

Primary outcome measure

  • Vineland Adaptive Behavior Scales, 3rd Edition [ Time Frame: 4 months ]

Central Contacts and Locations

Central contacts

Carrie Fassler

5138033580carrie.fassler@cchmc.org

Amie Duncan, PhD

amie.duncan@cchmc.org

Locations

University of North Carolina - Chapel Hill

Recruiting

Carrboro, North Carolina, United States, 27510

Contacts

Laura Klinger, Ph.D.

laura_klinger@med.unc.edu

Principal Investigator:

Laura Klinger, Ph.D.

Cincinnati Children's Hospital Medical Center

Recruiting

Cincinnati, Ohio, United States, 45229

Contacts

Carrie Fassler

5138033580carrie.fassler@cchmc.org

Principal Investigator:

Amie M Duncan, Ph.D.

More Information

Sponsor

Children's Hospital Medical Center, Cincinnati

Last update posted

Mar 18, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Children's Hospital Medical Center, Cincinnati on 2026-03-18.