Recruiting

MATAspire Intervention

Sponsor:

California State University, Northridge

Code:

NCT06553196

Conditions

Alcohol Use

Cannabis Use

Nicotine Use

Illicit Drug Use

Prescription Opioid Misuse

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

MATAspire Web-app

Study Details

Brief summary:

The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complete six weekly interactive modules using a smart device or computer. Each module is approximately 15-20 minutes long and focuses on select substances and coping strategies: (i) adaptive coping strategies, (ii) alcohol, (iii) cannabis, (iv) nicotine, (v) prescription drugs and opioids, (vi) final module. The modules are based on key theoretical constructs, behavior change strategies, and practical module components: attitudes (knowledge), perceived susceptibility (risk perceptions), and subjective norms (normative re-education). The intervention will be evaluated via a time series design using a sample of (\~1000 students) randomly assigned to either the intervention or the control conditions at a public institution in Southern California.

Conditions

Alcohol Use

Cannabis Use

Nicotine Use

Illicit Drug Use

Prescription Opioid Misuse

Study ID

NCT06553196

Start date

Aug 24, 2024

Status verified date

Mar, 2026

Completion date

Dec 31, 2028

Anticipated

Primary completion date

May 15, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Current Cal State Northridge (CSUN) matriculated students with active CSUN email
  • Age 18 and older

Exclusion Criteria:

  • Not currently a CSUN student
  • CSUN students under the age of 18 years
  • Have previously participated in this study
  • Identified as having an alcohol or substance use disorder (AUD or SUD) as determined by the brief Diagnostic and Statistical Manual of Mental Disorders (DSM) 5 screener

Study Design

Enrollment

1000 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Prevention group

Web-app with 6 weekly coping \& substance modules

no intervention: Control Group

No access to web-app

Interventions

MATAspire Web-app

Substance misuse prevention education and adaptive coping skills

Primary outcome measure

  • Change from baseline alcohol use behavior at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]
  • Change from baseline binge drinking at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]
  • Change from baseline cannabis use at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]
  • Change from baseline nicotine use at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]
  • Change from baseline electronic vape use products at 3 months [ Time Frame: Baseline and 90-days following intervention ]
  • Change from baseline non-prescribed prescription drug use behavior at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]
  • Change from baseline coping skills at 3 months [ Time Frame: Baseline and 90-days following intervention completion ]

Central Contacts and Locations

Central contacts

Bethany Rainisch, PhD, MPH

818-677-4081bethany.rainisch@csun.edu

Linn Dahlman, MPhil

818-677-5397mataspire@csun.edu

Locations

California State University, Northridge (CSUN)

Recruiting

Northridge, California, United States, 91330

Contacts

Bethany Rainisch, PhD, MPH

8186774081bethany.rainisch@csun.edu

Linn Dahlman

8186775397linn.dahlman@csun.edu

Principal Investigator:

Bethany Rainisch, PhD, MPH

More Information

Sponsor

California State University, Northridge

Last update posted

Oct 22, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-23. This information was provided to ClinicalTrials.gov by California State University, Northridge on 2026-10-22. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.