Recruiting

Observational Study

Sponsor:

Cleveland Dental Institute

Code:

NCT06553300

Conditions

Autotransplantation of Wisdom Teeth

Patelet Rich Fibrin

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Interventions

Autotransplantation with PRF

Autotransplatation Only

Study Details

Brief summary:

Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated. The success of autotransplantation is influenced by diverse factors, including root development stage, tooth morphology, surgical technique, extraoral duration, recipient socket shape, recipient bed vascularity, and periodontal ligament cell vitality. Preserving periodontal ligament quality and achieving tissue adaptation are pivotal for successful tooth transplantation. Successful donor tooth replacement is influenced by variables like fitting attempts, alveolus-root distance, extra-alveolar time, surgical skill, and extraction trauma intensity.

Conditions

Autotransplantation of Wisdom Teeth

Patelet Rich Fibrin

Study ID

NCT06553300

Start date

Jan 1, 2024

Status verified date

Jul, 2024

Completion date

Mar 31, 2025

Anticipated

Primary completion date

Oct 31, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Inclusion Criteria:

  • male and female
  • aged between 20 and 50 years
  • devoid of systemic ailments
  • complying with the study procedures
  • holding an Anesthesiologists classification of 1 or 2
  • possessing mandibular or maxillary immature wisdom teeth

Exclusion Criteria:

  • systemic diseases that might impede the healing process
  • Patients with pacemakers
  • Individuals harboring allergies to medications or antibiotics
  • active smokers
  • patients afflicted with periodontal diseases

Study Design

Enrollment

20 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Autotransplantation with PRF

active comparator: Autotrasplantation only

Interventions

Autotransplantation with PRF

Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth with the application of PRF

Autotransplatation Only

Autotransplantation of Wisdom teeth to the extracted socket of removed broken down posterior teeth.

Primary outcome measure

  • Radiographic success [ Time Frame: one year ]

Central Contacts and Locations

Central contacts

Nelza Baladi, DDS

n.baladi@cdiohio.org

Locations

Cleveland Dental Institute

Recruiting

Cleveland, Ohio, United States, 44128

Contacts

Waleed Elmallah, DDS

216-727-0234

Principal Investigator:

Luis M De la Rosa, DDS

More Information

Sponsor

Cleveland Dental Institute

Last update posted

Aug 14, 2024

Last verified

Jul, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Cleveland Dental Institute on 2024-08-14.