Recruiting

Observational Study

Sponsor:

University of Rochester

Code:

NCT06554353

Conditions

Breathing, Mouth

Lung Function Decreased

Dyspnea

Shortness of Breath

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Oscillometer

Study Details

Brief summary:

This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on Cardiopulmonary Exercise Testing in subjects who are experiencing shortness of breath.

Conditions

Breathing, Mouth

Lung Function Decreased

Dyspnea

Shortness of Breath

Study ID

NCT06554353

Start date

Oct 29, 2024

Status verified date

Oct, 2025

Completion date

Nov 30, 2026

Anticipated

Primary completion date

May 1, 2026

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Willingness to perform breathing test
  • Must be able to speak and understand English
  • Referred for Cardiopulmonary Exercise Testing

Exclusion Criteria:

  • Unable to provide consent or perform oscillometry test

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Arms

Subjects with dyspnea referred for Cardiopulmonary Exercise Testing

Subjects with unexplained dyspnea referred for Cardiopulmonary Exercise Testing.

Interventions

Oscillometer

The tremoFlo C-100 Airwave Oscillometry System is intended to measure respiratory system impedance using the Forced Oscillation Technique (FOT).

Primary outcome measure

  • Mean respiratory system resistance and reactance [ Time Frame: Single measurement, approximately day 1 ]

Central Contacts and Locations

Central contacts

PATRICK DONOHUE, MD

716-226-8429patrick_donohue@urmc.rochester.edu

Locations

Highland Hospital

Recruiting

Rochester, New York, United States, 14620

Contacts

PATRICK A DONOHUE, MD

5853416774patrick_donohue@urmc.rochester.edu

More Information

Sponsor

University of Rochester

Last update posted

Jun 3, 2026

Last verified

Oct, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Rochester on 2026-06-03.