Recruiting

Methadone

Sponsor:

University of Arizona

Code:

NCT06556602

Conditions

Opioid Use Disorder

Staff

Patients

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

MPACT

Study Details

Brief summary:

The trial of Methadone Patient Access to Collaborative Treatment (MPACT) will establish the impact of the intervention on patient outcomes of methadone treatment retention and in treatment overdose.

It will also establish the impact of patient and staff trauma symptoms and clinic practice change on MPACT intervention implementation.

Conditions

Opioid Use Disorder

Staff

Patients

Study ID

NCT06556602

Start date

Feb 5, 2026

Status verified date

Jul, 2026

Completion date

Jun 30, 2029

Anticipated

Primary completion date

Apr 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Staff providing methadone treatment services at the enrolled opioid treatment programs

Exclusion Criteria:

  • Patients receiving methadone treatment at the enrolled opioid treatment programs

Study Design

Enrollment

1080 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: MPACT Intervention

Enrolled clinic staff will be exposed to the MPACT intervention components over the trial period. This includes accredited training, clinic self assessment, reflective supervision for counseling/peer/case management staff, and wellness education with navigation to trauma symptoms assessment and resources including trauma treatment. Periodic surveys of staff and patients will be conducted to assess outcome measures (primary and secondary) and patient chart reviews will verify patient outcomes.

no intervention: Control for MPACT

Enrolled clinic staff will not receive any portion of the intervention. Periodic surveys of staff and patients will be conducted to assess outcome measures (primary and secondary) and patient chart reviews will verify patient outcomes.

Interventions

MPACT

Four components are part of this intervention: 1) accredited training about patient centered, trauma-informed care and the standard of care under the current federal regulation (42CFRpart8), 2) education about trauma and trauma symptoms including vicarious (work related) trauma and navigation to symptoms screening and resources including treatment, 3) reflective supervision for counseling, case management and peer staff, and 4) clinic self assessment for trauma-informed and patient centered care

Primary outcome measure

  • Days in Treatment to treatment interruption [ Time Frame: 18 months ]
  • Missed doses [ Time Frame: 20 months ]
  • In Treatment- Point in time [ Time Frame: 18 months ]
  • Number of patients reporting opioid overdoses while in methadone treatment [ Time Frame: 18 months ]

Central Contacts and Locations

Locations

University of Arizona College of Nursing

Recruiting

Tucson, Arizona, United States, 85714

Contacts

Beth Meyerson, PhD

520-626-0275bmeyerson@arizona.edu

Principal Investigator:

Beth Meyerson, PhD

More Information

Sponsor

University of Arizona

Last update posted

Jul 16, 2026

Last verified

Jul, 2026

Keywords

  • Methadone

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Arizona on 2026-07-16.