Recruiting

Exercise & Nutrition

Sponsor:

Roswell Park Cancer Institute

Code:

NCT06565260

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Exercise Intervention

Medical Device Usage and Evaluation

Nutritional Intervention

Physical Performance Testing

Questionnaire Administration

Study Details

Brief summary:

This clinical trial evaluates whether a supervised community-based exercise and nutrition program is usable and effective for improving cancer survivors' confidence for maintaining their physical activity and nutrition. Cancer survivors often experience problems with the musculoskeletal system (bones, joints, muscles, connective tissue), the cardiopulmonary system (heart, blood vessels and lungs) and the metabolic system (how the body's cells change food into energy) following treatment. There is substantial evidence that physical activity, diet, and weight management can improve quality of life (emotional and physical well-being) and physical fitness. Information gathered from this study may help researchers determine whether participating in a community-based exercise/nutrition training and education program may improve levels of fitness, cardiovascular health, and quality of life for cancer survivors.

Conditions

Hematopoietic and Lymphatic System Neoplasm

Malignant Solid Neoplasm

Study ID

NCT06565260

Start date

Sep 1, 2026

Status verified date

Jul, 2026

Completion date

Aug 30, 2029

Anticipated

Primary completion date

Aug 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18 years.
  • Have had a previous cancer diagnosis and completed all therapy OR are a caregiver for a patient who has had a previous cancer diagnosis.
  • Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related interventions.

Exclusion Criteria:

  • Have uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia including atrial fibrillation (AFIB), multiple myeloma, or psychiatric illness/social situations that would limit compliance with study requirements.
  • Have orthopedic or neuromuscular disorders or arthritis that preclude participation in exercise.
  • Are pregnant or nursing.
  • History of a stem cell transplant.
  • Currently on steroids.
  • Unwilling or unable to follow protocol requirements.
  • Any condition which in the investigator's opinion deems the participant an unsuitable candidate to participate in the study.

Study Design

Enrollment

150 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Supportive Care (exercise/nutrition program)

Patients participate in a supervised, community-based exercise program consisting of aerobic and resistance exercise over 45-60 minutes BIW for 12 weeks. Beginning at week 2, patients also receive nutrition education and training QW for 10 weeks. Patients also wear an activity tracker throughout the study.

Interventions

Exercise Intervention

Participate in exercise program

Medical Device Usage and Evaluation

Wear an activity tracker

Nutritional Intervention

Participate in nutrition program

Physical Performance Testing

Ancillary studies

Questionnaire Administration

Ancillary studies

Primary outcome measure

  • Proportion of patients still on study (Feasibility) [ Time Frame: At the end of the 12 week intervention ]
  • Percentage of patients on study after 12 weeks who complete at least 70% of intervention activities (Acceptability) [ Time Frame: At 12 weeks ]
  • Patient satisfaction (Acceptability) [ Time Frame: Baseline to 3 months post-intervention ]

Central Contacts and Locations

Locations

Roswell Park Cancer Institute

Recruiting

Buffalo, New York, United States, 14263

Contacts

Andrew D. Ray

716-845-2381Andrew.Ray@roswellpark.org

Principal Investigator:

Andrew D. Ray

More Information

Sponsor

Roswell Park Cancer Institute

Last update posted

Jul 29, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Roswell Park Cancer Institute on 2026-07-29.