Recruiting

Personalized Model

Sponsor:

VA Office of Research and Development

Code:

NCT06580457

Conditions

Substance Use Disorder

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Personal Causal Model + Personalized Feedback

Study Details

Brief summary:

An important part of substance use treatment for many people is learning what triggers their substance use and urges, and how they can better manage those triggers. In this study, the investigators will generate a model for each individual that shows likely causal links between their substance use, urges, and comorbid symptoms (e.g., anxiety, depression, and PTSD), and the investigators will examine these models as a group to draw conclusions about common causes for substance use (and recovery) among Veterans with substance use disorders. The investigators will also test whether receiving a personal model and clinical feedback improves substance use disorder and comorbid symptom outcomes. Results will include both patient-reported and statistically-determined causes of substance use for individuals and groups, clinical impact of a personalized model and feedback session, and participant feedback about the relevance of this study and intervention.

Conditions

Substance Use Disorder

Study ID

NCT06580457

Start date

Oct 1, 2025

Status verified date

Jan, 2026

Completion date

Mar 29, 2030

Anticipated

Primary completion date

Oct 1, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Inclusion criteria for this study are intended to include most Veterans with SUD
  • inclusion criteria are current probable SUD as indicated by:

  • a clinical score on the alcohol use disorders identification test (AUDIT) or drug use disorders identification test (DUDIT)
  • past-month substance use
  • a reliable access to a smartphone, tablet, or other device with capability of accessing and completing surveys throughout the day

  • this will exclude those who are currently completing inpatient treatment

Exclusion Criteria:

  • exclusion criteria are being under the influence of a judgment-impairing substance at the time of consent (e.g., cannabis, alcohol, illicit opioids)

  • participants will be invited to return another day
  • being legally compelled to complete treatment
  • or being under civil commitment

  • due to lack of ability to give autonomous consent in these situations

Study Design

Enrollment

74 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Intervention

Receive the personal causal model with a 1-hour, live clinical feedback session.

no intervention: Control

No clinical feedback session. Personal causal models will be provided at the end of the study for those who wish to receive them.

Interventions

Personal Causal Model + Personalized Feedback

Receive a personal causal model of one's personalized causes of substance use/urges, along with a 1-hour, live clinical feedback session to suggest how to apply these insights to one's own recovery.

Primary outcome measure

  • Substance use [ Time Frame: 4-, 8-, and 12-week follow-ups ]
  • Substance-related problems [ Time Frame: 4-, 8-, and 12-week follow-ups ]

Central Contacts and Locations

Central contacts

Brittany Stevenson, PhD

(612) 467-3023Brittany.Stevenson@va.gov

Kelvin O Lim, MD

(612) 467-3323kelvin.lim@va.gov

Locations

Minneapolis VA Health Care System, Minneapolis, MN

Recruiting

Minneapolis, Minnesota, United States, 55417-2309

Contacts

Brittany Stevenson, PhD

612-467-3023Brittany.Stevenson@va.gov

Kelvin O Lim, MD

(612) 467-3323kelvin.lim@va.gov

Principal Investigator:

Brittany Stevenson, PhD

More Information

Sponsor

VA Office of Research and Development

Last update posted

Jan 15, 2026

Last verified

Jan, 2026

Keywords

  • substance use disorder
  • precision medicine
  • ecological momentary assessment

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Office of Research and Development on 2026-01-15.