Recruiting

Quit Smoking

Sponsor:

Masonic Cancer Center, University of Minnesota

Code:

NCT06584929

Conditions

Smoking Cessation

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Interventions

Nicoderm CQ nicotine patch

Nicorette Nicotine Lozenges

Study Details

Brief summary:

Understanding ways to help people who live in rural areas quit smoking is a public health priority. quitting smoking among rural people who smoke is a critical public health concern. People in rural areas smoke at higher rates than those in urban areas, experience high rates of smoking caused cancers and deaths. We are recruiting rural people from around the country to better understand how different quit smoking methods can improve a person's chances of successfully quitting smoking.

Conditions

Smoking Cessation

Study ID

NCT06584929

Start date

Mar 17, 2026

Status verified date

Jul, 2026

Completion date

Aug 31, 2029

Anticipated

Primary completion date

Oct 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • ≥ 21 years
  • smoke ≥ 5 cigarettes per day
  • daily access to their own iPhone/Android smartphone or tablet

Exclusion Criteria:

  • past 30-day NRT use or contraindications listed on the NRT labels
  • currently pregnant/breastfeeding

Study Design

Enrollment

544 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Intervention Condition

Weekly text and email messages referring to Smokefree.gov, NRT Starter kit, free 2-week supply of patches (Nicoderm CQ in either 21 or 14 mg nicotine) and lozenges (Nicorette Nicotine Lozenges, Mint Flavor in either 4 or 2 mg nicotine) with NRT education plus referral to where to request more NRT.

no intervention: Control Condition

Weekly text and email messages referring to Smokefree.gov

no intervention: RHE - Intervention Condition

Weekly text and email messages on reduced harm or exposure (RHE) tobacco products.

Interventions

Nicoderm CQ nicotine patch

Two week supply provided to participants on study.

Nicorette Nicotine Lozenges

Two week supply provided to participants on study.

Primary outcome measure

  • Number of participants abstinent from all combustible tobacco products [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Dana Carroll, PhD

612-624-4511dcarroll@umn.edu

Locations

Masonic Cancer Center

Recruiting

Minneapolis, Minnesota, United States, 55455

Contacts

Dana Carroll, PhD, MPH

612-624-4610tobacco@umn.edu

More Information

Sponsor

Masonic Cancer Center, University of Minnesota

Last update posted

Jul 27, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Masonic Cancer Center, University of Minnesota on 2026-07-27.