Recruiting

Deep Brain Stimulation

Sponsor:

Boston Children's Hospital

Code:

NCT06585618

Conditions

Dystonia

Epilepsy in Children

Cerebral Palsy

Tourette Syndrome

Obsessive-Compulsive Disorder

Eligibility Criteria

Sex: All

Age: 0 - 18

Healthy Volunteers: Not accepted

Study Details

Brief summary:

There is limited data on outcomes for children who have undergone deep brain stimulation (DBS) for movement disorders, and individual centers performing this surgery often lack sufficient cases to power research studies adequately. This study aims to develop a multicenter pediatric DBS registry that allows multiple sites to share clinical pediatric DBS data. The primary goals are to enable large-scale, well-powered analyses of the safety and efficacy of DBS in the pediatric population and to further explore and refine DBS as a therapeutic option for children with dystonia and other hyperkinetic movement disorders. Given the current scarcity of evidence available to clinicians, this centralized multicenter repository of clinical data is critical for addressing key research questions and improving clinical practice for pediatric DBS.

Conditions

Dystonia

Epilepsy in Children

Cerebral Palsy

Tourette Syndrome

Obsessive-Compulsive Disorder

Study ID

NCT06585618

Start date

Jul 30, 2024

Status verified date

Mar, 2026

Completion date

Jul 30, 2029

Anticipated

Primary completion date

Jul 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 18

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Female or male patients between ages of 0-18 years.
  • Having received or scheduled to receive DBS for any neurological movement disorder.
  • Parents or legal guardians are able to provide written consent for prospective enrollment.

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Development of a Multi-Center Pediatric DBS Registry [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Locations

Boston Children's Hospital

Recruiting

Boston, Massachusetts, United States, 02215

Contacts

More Information

Sponsor

Boston Children's Hospital

Last update posted

Mar 18, 2026

Last verified

Mar, 2026

Keywords

  • Deep Brain Stimulation
  • DBS
  • movement disorder
  • movement disorders in children
  • dystonia
  • chorea
  • dyskinesia
  • epilepsy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Boston Children's Hospital on 2026-03-18.