Recruiting

Resistance-band Training & Creatine

Sponsor:

University of Regina

Code:

NCT06606704

Conditions

Aging

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Interventions

Creatine Bolus 5

Creatine Bolus 3

Creatine Intermittent 5

Placebo

Study Details

Brief summary:

The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

Conditions

Aging

Study ID

NCT06606704

Start date

Aug 20, 2024

Status verified date

Sep, 2024

Completion date

Jul 30, 2025

Anticipated

Primary completion date

Jul 30, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • if you are 50 years of age and older
  • if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.

Exclusion Criteria:

  • if you have taken creatine supplements within 30 days prior to the start of the study
  • if you have pre-existing allergies to the placebo (corn-starch maltodextrin).

Study Design

Enrollment

52 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Creatine Bolus 5

experimental: Creatine Bolus 3

experimental: Creatine Intermittent 5

placebo comparator: Placebo

Interventions

Creatine Bolus 5

(Serving 1: 5 grams of creatine + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).

Creatine Bolus 3

(Serving 1: 3 grams of creatine + 5 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).

Creatine Intermittent 5

(Serving 1: 2.5 grams of creatine + 5.5 grams of placebo in the morning, Serving 2: 2.5 grams of creatine + 5.5 grams of placebo at least 6 hours after Serving 1).

Placebo

(Serving: 8 grams of placebo in the morning; Servings 2: 8 grams of placebo at least 6 hours after Serving 1).

Primary outcome measure

  • Whole-body lean mass (kg) [ Time Frame: baseline, week 16 ]
  • Muscle Hypertrophy (cm) [ Time Frame: baseline, week 16 ]
  • Strength (kg) [ Time Frame: baseline, week 16 ]
  • Endurance (number of repetitions to fatigue) [ Time Frame: baseline, week 16 ]
  • Power (feet) [ Time Frame: baseline, week 16 ]
  • Balance (Centre of Pressure) [ Time Frame: baseline, week 16 ]
  • Gait Speed (meters) [ Time Frame: baseline, week 16 ]

Central Contacts and Locations

Central contacts

Darren Candow

306-585-4906Darren.Candow@uregina.ca

Locations

University of Regina

Recruiting

Regina, Saskatchewan, Canada, S4S4H4

Contacts

Darren G Candow, PhD

3062090280Darren.Candow@uregina.ca

More Information

Sponsor

University of Regina

Last update posted

Sep 23, 2024

Last verified

Sep, 2024

Keywords

  • Aging
  • Creatine
  • Resistance-Bands
  • Muscle
  • Strength

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Regina on 2024-09-23.