Recruiting

Physical Activity

Sponsor:

Children's Hospital of Philadelphia

Code:

NCT06624358

Conditions

Chronic Kidney Diseases

Eligibility Criteria

Sex: All

Age: 13 - 18

Healthy Volunteers: Not accepted

Interventions

Increase Physical Activity

Study Details

Brief summary:

The goal of this is to test the efficacy of a 12-week physical activity intervention in 64 adolescents with CKD.

Conditions

Chronic Kidney Diseases

Study ID

NCT06624358

Start date

Sep 30, 2025

Status verified date

Oct, 2025

Completion date

Dec, 2028

Anticipated

Primary completion date

Jun, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 13 - 18

Healthy Volunteers: Not accepted

Inclusion criteria:

For adolescent participants:

1. Males or females age 13 - 18 years
2. Diagnosis of CKD stage II - V not yet on dialysis or with a transplant
3. English proficiency
4. Parental/guardian permission (informed consent), and if applicable, child assent

For caregiver participants:

1. Parent/legal guardian of an enrolled adolescent participant
2. English proficiency

Exclusion Criteria:

For adolescent participants:

1. Pregnant or lactating
2. Non-ambulatory
3. Have high physical activity at baseline (>45 min/day of MVPA)
4. Provide <2 days of physical activity data during the run-in period
5. Have a condition, such as heart or lung disease, that preclude safely engaging in physical activity
6. Have received a solid organ transplant
7. Have limited English proficiency
8. Are on dialysis
9. In the opinion of the investigator, are unable to comply with the requirements of the study protocol or are unsuitable for the study for any reason

For caregivers participants:

1\. Limited English proficiency

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Factorial

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Fixed step goal only

This intervention designed to test if fixed step goals improve physical activity participation.

experimental: Fixed step goal with feedback

This intervention designed to test if fixed step goals and/or daily feed back improve physical activity participation.

experimental: Fixed step goal with financial incentives

This intervention designed to test if fixed step goals and/or financial incentives improve physical activity participation.

experimental: Fixed step goal with financial incentive and feedback

This intervention designed to test if fixed step goals and/or financial incentives and/or daily feedback improve physical activity participation.

experimental: Ramped Step goals

This intervention designed to test if ramped step goals improve physical activity participation.

experimental: Ramped step goals with feedback

This intervention designed to test if ramped step goals and/or daily feedback improve physical activity participation.

experimental: Ramped step goal with financial incentive

This intervention designed to test if ramped step goals and/or financial incentive improve physical activity participation.

experimental: Ramped step goal with financial incentive and feedback

This intervention designed to test if ramped step goals and/or financial incentive and/or daily feedback improve physical activity participation.

experimental: Personalized plan with fixed step goal

This intervention designed to test if personalized exercise plan and/or fixed step goal improves physical activity participation.

experimental: Personalized plan with fixed step goal and feedback

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or daily feedback improves physical activity participation.

experimental: Personalized plan with fixed step goal and financial incentive

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or financial incentive improves physical activity participation.

experimental: Personalized plan with fixed step goal and financial incentive and feedback

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or financial incentive and/or daily feedback improves physical activity participation.

experimental: Personalized plan with ramped step goal

This intervention designed to test if personalized exercise plan and/or fixed step goal improves physical activity participation.

experimental: Personalized plan with ramped step goal and feedback

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or daily feedback improves physical activity participation.

experimental: Personalized plan with ramped step goal and financial incentive

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or financial incentive improves physical activity participation.

experimental: Personalized plan with ramped step goal and financial incentive and feedback

This intervention designed to test if personalized exercise plan and/or fixed step goal and/or financial incentive and/or daily feedback improves physical activity participation.

Interventions

Increase Physical Activity

Behavioral interventions to improve physical activity

Primary outcome measure

  • Change in time spent in moderate to vigorous physical activity (minutes/day) [ Time Frame: pre 12 week intervention and post 12 week intervention ]

Central Contacts and Locations

Central contacts

Locations

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Principal Investigator:

Amy Kogon, MD, MPH

More Information

Sponsor

Children's Hospital of Philadelphia

Last update posted

Oct 2, 2025

Last verified

Oct, 2025

Keywords

  • chronic kidney disease
  • CKD

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Children's Hospital of Philadelphia on 2025-10-02.