Recruiting

Alcohol Consumption

Sponsor:

University of Southern California

Code:

NCT06627803

Conditions

Alcohol Consumption

Alcohol Abuse/Dependence

Eligibility Criteria

Sex: All

Age: 21 - 28

Healthy Volunteers: Accepted

Interventions

Alcohol (Oral)

Study Details

Brief summary:

The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults. About 200 young adults who drink alcohol frequently will take part in the study. This research is being funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

Participation involves one in-person screening session with a same-sex platonic friend. Then participants will complete four in-person laboratory sessions where they will drink beverages containing alcohol or no alcohol. After completion of the laboratory sessions, participants will complete smartphone surveys for 28 days. Lastly, they will complete follow-up surveys 6 months and 12 months post-study enrollment.

Conditions

Alcohol Consumption

Alcohol Abuse/Dependence

Study ID

NCT06627803

Start date

Feb 20, 2025

Status verified date

Aug, 2025

Completion date

Aug 31, 2029

Anticipated

Primary completion date

Aug 31, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21 - 28

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 21-28 years of age
  • Drink regularly (1+ times/week) with a same-sex platonic friend that also meets eligibility and is willing to participate
  • Regular alcohol use (3+ times/week) with at least one binge drinking episode (5+ drinks \[male\] or 4+ drinks \[female\] in about 2 hours) in the past month
  • BMI of 18-30
  • Own a smart device operating on the iOS or Android operating system
  • Fluent in English

Exclusion Criteria:

  • Pregnancy or breastfeeding or intent to get pregnant in the next 60 days (females)
  • medical conditions counter-indicated for alcohol administration
  • seeking treatment for alcohol use

Study Design

Enrollment

200 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Laboratory alcohol administration with longitudinal follow-ups

All participants will be in this single arm, which consists on behavioral testing of alcohol administration in the lab, followed by longitudinal follow-ups using Ecological Momentary Assessment and surveys.

Interventions

Alcohol (Oral)

Participants will drink a beverage that will have alcohol or no alcohol. The amount of alcohol consumed will be similar to consuming around 3-4 drinks, with breath alcohol concentration peaking at or around the legal limit for driving (0.08%).

Primary outcome measure

  • Drug Effect Questionnaire (DEQ) [ Time Frame: The DEQ will be assessed 30 minutes before alcohol administration, and again 30, 60, 90, 120, 180, and 240 minutes after alcohol administration during each session. ]
  • Biphasic Alcohol Effects Scale (BAES) [ Time Frame: The BAES will be assessed 30 minutes before alcohol administration, and again 30, 60, 90, 120, 180, and 240 minutes after alcohol administration during each session. ]
  • Quantity of Alcohol Use during Ecological Momentary Assessment [ Time Frame: Quantity of Alcohol Use will be assessed daily for 28 days. ]
  • Past 30-day Alcohol Use during Follow-Up [ Time Frame: Past 30-day alcohol use will be assessed 6 and 12 months after the initial laboratory sessions. ]

Central Contacts and Locations

Central contacts

Matt G Kirkpatrick, PhD

323-442-8221mgkirkpa@usc.edu

Locations

University of Southern California

Recruiting

Los Angeles, California, United States, 90032

Contacts

Matt G Kirkpatrick

323-442-8221mgkirkpa@usc.edu

Principal Investigator:

Matt G Kirkpatrick, PhD

More Information

Sponsor

University of Southern California

Last update posted

Aug 12, 2025

Last verified

Aug, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Southern California on 2025-08-12.