Recruiting

Flavored Cigarillos

Sponsor:

University of Oklahoma

Code:

NCT06668350

Conditions

Cigarillo Flavor

Eligibility Criteria

Sex: All

Age: 18 - 34

Healthy Volunteers: Accepted

Interventions

Smoking outcomes

Study Details

Brief summary:

This multi-method project will recruit young adults who currently use cigarillos and examine the effects of different flavored cigarillo types (concept, characterizing, tobacco) on three measures of tobacco product appeal: subjective effects (e.g., taste, enjoyment, satisfaction, reward), actual smoking behavior (e.g., number of puffs), and tobacco product purchases via a simulated experimental tobacco marketplace.

Conditions

Cigarillo Flavor

Study ID

NCT06668350

Start date

Jun 27, 2025

Status verified date

Aug, 2025

Completion date

Jun 30, 2029

Anticipated

Primary completion date

Feb 1, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 34

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Ages18 to 34
  • Smoke a little cigar or cigarillo (LCCs) "some days" or "everyday" (verified by brand name of the product);
  • Ability to read English at an 8th grade level or higher; and
  • No immediate plans to quit using tobacco
  • > 1 prior experience, even 1 puff, with a flavored tobacco product
  • U.S. Citizen or permanent resident of the United States.

Exclusion Criteria:

  • Current use of nicotine replacement therapy (NRT) or stop smoking medication;
  • Pregnant, planning to become pregnant, or currently breastfeeding;
  • Past or current self-reported clinically significant heart disease or hypertension, or other smoking-related disease (by history) that preclude successful study completion;
  • Inability to abstain from nicotine/tobacco products for at least 12 hours prior to lab sessions
  • Report using the study cigarillo brand as their preferred brand (as this will likely unduly influence their perceptions)
  • Unwillingness to use "untipped" (e.g., plastic or wood tip) little cigars/cigarillos.

Study Design

Enrollment

190 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Concept flavored cigarillo

Participants will smoke a concept flavored cigarillo in the lab

experimental: Characterizing flavored cigarillo

Participants will smoke a characterizing flavored cigarillo

experimental: Tobacco flavored cigarillo

Participants will smoke a tobacco flavored cigarillo

Interventions

Smoking outcomes

Participants will be assessed on several smoking outcomes including puffing behavior, subjective effects, and exhaled carbon monoxide

Primary outcome measure

  • Puff volume [ Time Frame: From enrollment to the end of the study at 6 weeks ]
  • Subjective effects from smoking [ Time Frame: From enrollment to the end of the study at 6 weeks ]
  • Exhaled carbon monoxide [ Time Frame: From enrollment to the end of the study at 6 weeks ]

Central Contacts and Locations

Central contacts

Project Manager

1-405-271-7759heal-lab@ouhsc.edu

Locations

TSET Health Promotion Research Center

Recruiting

Oklahoma City, Oklahoma, United States, 73012

Contacts

Project Manager

405-271-1903heal-lab@ouhsc.edu

Principal Investigator:

Amy Cohn, PhD

More Information

Sponsor

University of Oklahoma

Last update posted

Aug 17, 2025

Last verified

Aug, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Oklahoma on 2025-08-17.