Recruiting

Active Driver Training & Control

Sponsor:

VA Office of Research and Development

Code:

NCT06672107

Conditions

Stroke

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Active Driver Training Intervention

Control Intervention

Study Details

Brief summary:

One hundred Veteran stroke survivors will participate in both an Active Driver Training intervention and a Control intervention in a fully interactive driving simulator. In addition, all participants will complete pre- and post-intervention driving assessments in the driving simulator to measure driving performance and types of driving errors committed. Half the participants will receive the Active Driver Training first, whereas the other half will receive the Control intervention first. Each Active Driver Training session will provide targeted practice and feedback on each of four unique driving skills including: speed management, collision avoidance, lane positioning, and dashboard attention. The Control intervention will be matched for total time but will only provide extra familiarization with the operation of the driving simulator, with no skill-specific practice. It is predicted that the Active Driver Training Intervention will result in improved driving performance, relative to the Control condition. In addition, after a delay period of at least 6 months, all participants will be re-assessed in the driving simulator and will complete a survey to capture changes in driving status.

Conditions

Stroke

Study ID

NCT06672107

Start date

Nov 17, 2025

Status verified date

Apr, 2026

Completion date

Sep 30, 2029

Anticipated

Primary completion date

Jun 30, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • U.S. Veterans
  • History of a unilateral stroke (at least 3 months post-onset)
  • Ages 40-80
  • pre-morbidly right hand dominant
  • prior driving experience/U.S. driver's license

Exclusion Criteria:

  • History of other neurologic illness (e.g., TBI, dementia, epilepsy, Parkinson's, etc.)
  • History of severe psychiatric illness (e.g., schizophrenia or other psychotic disorders)
  • Recent substance abuse/dependence disorder (< 1 year)
  • Non-Veteran status

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Right hemisphere stroke

Participants with a history of a unilateral stroke affecting the right cerebral hemisphere.

Left hemisphere stroke

Participants with a history of a unilateral stroke affecting the left cerebral hemisphere.

Interventions

Active Driver Training Intervention

simulated driver training focusing on practice of 4 specific driving skills including lane positioning, speed management, collision avoidance, and dashboard attention

Control Intervention

pre-scripted familiarization with driving simulator controls in the absence of any complex driving scenarios, decision making requirements, or feedback pertaining to driving skills

Primary outcome measure

  • Driving Score-post Active Training Intervention [ Time Frame: 4 weeks ]
  • Driving Score- post Control Intervention [ Time Frame: 4 weeks ]
  • 6-mo followup Driving Score [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Krista S Parker, PhD BA

(925) 372-2513Krista.Parker@va.gov

Juliana V Baldo, PhD

(925) 372-4649Juliana.Baldo@va.gov

Locations

VA Northern California Health Care System, Mather, CA

Recruiting

Sacramento, California, United States, 95655-4200

Contacts

Jerry L Nadler, MD

(916) 843-2776Jerry.Nadler@va.gov

Juliana V Baldo, PhD

(925) 372-4649Juliana.Baldo@va.gov

Principal Investigator:

Krista Schendel Parker, PhD BA

More Information

Sponsor

VA Office of Research and Development

Last update posted

Apr 24, 2026

Last verified

Apr, 2026

Keywords

  • Stroke
  • Brain injury
  • Driving
  • Cognition

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Office of Research and Development on 2026-04-24.