Recruiting

AI Chatbot vs. Handouts

Sponsor:

Virginia Commonwealth University

Code:

NCT06682494

Conditions

Oral Cancer

Chatbot

Patient Education

Prevention

Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Traditional Education

AI-powered Chatbox

Study Details

Brief summary:

To evaluate the impact of AI-powered chatbot interactions versus traditional educational handouts on increasing participants' knowledge of oral cancer and its prevention

Conditions

Oral Cancer

Chatbot

Patient Education

Prevention

Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer

Study ID

NCT06682494

Start date

Sep 24, 2025

Status verified date

May, 2026

Completion date

Oct 31, 2027

Anticipated

Primary completion date

Oct 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Identify as African American as defined by the US Census
  • Participants must be able to read, speak, and write in English

Exclusion Criteria:

  • Individuals who cannot physically or mentally participate in the research project will be excluded
  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Prisoners

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

active comparator: Traditional Educational Materials

Receiving oral cancer educational materials (handouts from trusted sources such as the Centers for Disease Control (CDC) and American Cancer Association (ACA) and other reliable health education resources.

experimental: Engaging with an AI-powered Chatbot

AI-powered chatbox designed specifically for oral cancer education. The chatbot is programmed to provide accurate information on oral cancer risks, symptoms, preventive measures, and the importance of regular dental check-ups.

Interventions

Traditional Education

Participants will receive traditional educational handouts focusing on increasing awareness of oral cancer risks, preventive strategies, and the importance of regular dental check-ups. Participants will be provided time to read the handouts based on calculated reading time.

AI-powered Chatbox

The chatbot interaction will be initiated through a provided link, allowing participants to access information and ask questions related to oral health and cancer prevention. The chatbot is programmed to provide accurate information on oral cancer risks, symptoms, preventive measures, and the importance of regular dental check-ups. Participants will be encouraged to interact with the chatbot for a specified duration

Primary outcome measure

  • Compare participant retention rates between the AI-powered tool arm and the conventional educational material arm [ Time Frame: Baseline, and post intervention (3 months) ]
  • Evaluate the impact of AI-powered chatbot interactions versus traditional educational handouts on knowledge and behavior [ Time Frame: Baseline, and post intervention (3 months) ]
  • Investigate socio-demographic factors that affect oral cancer knowledge in the African American population [ Time Frame: Baseline, and post intervention (3 months) ]
  • Evaluate the acceptability of AI-powered chatbot interactions versus traditional educational handouts [ Time Frame: Baseline, and post intervention (3 months) ]

Central Contacts and Locations

Central contacts

Tamas Gal, Ph.D

804-628-2123Tamas.Gal@vcuhealth.org

Locations

Virginia Commonwealth University

Recruiting

Richmond, Virginia, United States, 23298

Contacts

Tamas Gal, Ph.D

804-628-2123Tamas.Gal@vcuhealth.org

Principal Investigator:

Tamas Gal, Ph.D

More Information

Sponsor

Virginia Commonwealth University

Last update posted

May 8, 2026

Last verified

May, 2026

Keywords

  • AI-powered Chatbox
  • Oral cancer prevention
  • Socio-economic barriers

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Virginia Commonwealth University on 2026-05-08.