Recruiting

Pivotal Response Treatment

Sponsor:

Stanford University

Code:

NCT06690255

Conditions

Autism Spectrum Disorder

Eligibility Criteria

Sex: All

Age: 2 - 5

Healthy Volunteers: Not accepted

Interventions

Pivotal Response Treatment

Study Details

Brief summary:

The goal of this clinical trial is to understand if an online course in Spanish can help Spanish-speaking parents use Pivotal Response Treatment (PRT) to support language and social skills in young children with Autism Spectrum Disorder (ASD). This study aims to reach families who may have trouble accessing autism services due to language, location, or cost barriers. The main questions it hopes to answer are:

  • Can Spanish-speaking parents learn to effectively use PRT techniques to support their child's communication?
  • Does this training improve children's language and social interactions?

Researchers will evaluate the effectiveness of the online course for parents who participate in regular virtual check-ins and submit videos showing their practice with PRT.

Participants in the study will:

  • Complete online lessons over 12 weeks that teach PRT methods, specifically designed for Spanish-speaking parents
  • Meet with a research team member every few weeks by phone or video to ask questions and receive feedback
  • Provide video recordings of interactions with their child to track progress
  • Complete brief surveys about their experience and child's communication abilities

By focusing on Spanish-speaking families, this study aims to increase access to effective autism support and reduce gaps in care. Researchers hope the findings will help develop better resources for families facing similar barriers and improve language and social outcomes for children with autism.

Conditions

Autism Spectrum Disorder

Study ID

NCT06690255

Start date

Jun 17, 2026

Status verified date

Jun, 2026

Completion date

Dec 15, 2030

Anticipated

Primary completion date

Dec 15, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 2 - 5

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Children aged 2 to 5 years, 11 months at the time of consent
  • Diagnosis of Autism Spectrum Disorder (ASD), confirmed through medical records and/or parent questionnaire
  • Significant language delay, indicated by scores 2 standard deviations (SD) below the average for ages 2 and 3, or 3 SD below the average for ages 4 and 5 on the Vineland-3 Communication subscale or Expressive V-scale
  • A Spanish-speaking parent or primary caregiver available to consistently participate in study activities and implement PRT in Spanish
  • Stable on any psychotropic medications or biomedical interventions for at least 1 month before baseline, with no anticipated changes during the study
  • Consistent treatment or intervention services (such as ABA, Floortime, or speech therapy) and stable school placement for at least 1 month before baseline, with no expected changes
  • Limited to no more than 60 minutes of one-on-one speech therapy per week

Exclusion Criteria:

  • Primary language of the child or parent is not Spanish
  • Either the child or parent has a severe psychiatric disorder or an unstable medical condition
  • Prior exposure to or adequate trial of Pivotal Response Treatment, resulting in the parent achieving fidelity in PRT implementation at baseline
  • The child is currently receiving more than 15 hours of one-on-one Applied Behavior Analysis (ABA) therapy per week

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Spanish PRT Online

Participating parents will receive access to a 12-week online course designed to teach Pivotal Response Treatment (PRT) strategies in Spanish. The course includes 10 instructional lessons and check-ins with a researcher via secure videoconference.

Interventions

Pivotal Response Treatment

PRT will target functional communication abilities

Primary outcome measure

  • Change in Parent Fidelity of PRT Implementation from Baseline to Week 12 [ Time Frame: Baseline, Week 12 ]

Central Contacts and Locations

Central contacts

Grace Gengoux, Ph.D.

6507235511ggengoux@stanford.edu

Ty Vernon, Ph.D.

tyvernon@ucsb.edu

Locations

Stanford University

Recruiting

Palo Alto, California, United States, 94305

Contacts

Robin Libove

650-736-1235autismdd@stanford.edu

Principal Investigator:

Grace Gengoux, PhD

More Information

Sponsor

Stanford University

Last update posted

Jun 22, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Stanford University on 2026-06-22.