Recruiting
Phase 3

Electronic Harm Reduction

Sponsor:

University of Washington

Code:

NCT06702007

Conditions

Alcohol Use Disorder

Harm Reduction

Housing First (eg. Permanent Supportive Housing)

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Interventions

eHaRT-A

Study Details

Brief summary:

The goal of this project is to transform a successful, face-to-face harm-reduction treatment (HaRT-A) into a digital format, creating eHaRT-A. This new platform is specifically designed for people who have experienced homelessness and an alcohol use disorder (AUD), living within the framework of permanent, supportive, Housing First (HF) facilities. We hypothesize eHaRT-A will be more effective than the standard HF services in reducing alcohol-related harm and improving the overall quality of life for participants.

Conditions

Alcohol Use Disorder

Harm Reduction

Housing First (eg. Permanent Supportive Housing)

Study ID

NCT06702007

Start date

Jan 20, 2025

Status verified date

Jul, 2025

Completion date

Aug 31, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Being at least 21 years of age
  • Speak English fluently
  • Currently a registered client at one of the Housing First sites
  • Currently drinking (has used alcohol in the past 2 weeks)
  • Meeting criteria for "current" (e.g., past-year) AUD according to the Diagnostic and Statistical Manual of Mental Health Disorders, Fifth Edition (determined as scoring >= 2 on the SCID-5-CV)

Exclusion Criteria:

  • Enrollment in any related treatment studies (including studies by this research team)
  • Refusal or inability to consent
  • Constituting a risk to the safety and security of residents or staff

Study Design

Enrollment

160 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

no intervention: Housing First As Usual

Housing First as usual includes housing provision and management, fulfillment of basic needs (e.g., food, clothing), nursing/medical services and case management.

experimental: Housing First + eHaRT-A

HaRT-A comprises three concrete treatment components: 1) measurement and participant-led tracking of indicators of alcohol-related harm (e.g., number of drinks, blackouts), 2) elicitation of harm-reduction and health related quality of life (HRQoL) goals (e.g., drink slower, eat healthier, reconnect with family), and 3) discussion of safer-drinking strategies (e.g., taking B-complex vitamins, eating prior to or during alcohol use, avoiding mixing alcohol and other drugs). HaRT-A honors community representation within harm-reduction intervention development and acknowledges the larger forces (familial, community, geopolitical) at play in substance use, thus emphasizing the wisdom of the participant in defining their own pathway to recovery.

Interventions

eHaRT-A

Adaptation of the Harm Reduction Treatment for Alcohol (HaRT-A) into a digital telehealth platform facilitating harm reduction treatment via patient-provider video sessions (eHaRT-A). eHaRT-A will include the three treatment components from the efficacious HaRT-A. eHaRT-A will be delivered during one-on-one sessions through video conferencing with interactive features (i.e., personalized feedback tracked over time and screen sharing).

Primary outcome measure

  • Change in physical and mental-health related quality of life from baseline through 3-month follow-up as measured by the EQ-5D-5L [ Time Frame: Baseline through 3-month follow-up ]
  • Change in typical and peak alcohol quantity consumed from baseline through 3-month follow-up as assessed by the AQUA. [ Time Frame: Baseline through 3-month follow-up ]
  • Change in alcohol-related harm from baseline through 3-month follow-up as assessed by the SIP-2R. [ Time Frame: Baseline to 3-month follow-up ]
  • Feasibility of eHaRT-A within Housing First [ Time Frame: Baseline to 3-month follow-up. ]

Central Contacts and Locations

Central contacts

Emily Taylor

206-744-1873emt07@uw.edu

Tessa Frohe, PhD

frohe06@uw.edu

Locations

Downtown Emergency Service Center

Recruiting

Seattle, Washington, United States, 98104

More Information

Sponsor

University of Washington

Last update posted

Jul 8, 2025

Last verified

Jul, 2025

Keywords

  • Telehealth
  • Alcohol-Related Harm
  • Community Based Participatory Research
  • Lived experience of chronic homelessness

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Washington on 2025-07-08.