Recruiting

Motor Skill Detection

Sponsor:

National Institute of Neurological Disorders and Stroke (NINDS)

Code:

NCT06707207

Conditions

Healthy

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

Study Details

Brief summary:

Background:

Many tasks people do every day require a series of individual movements. Control over these movements is called motor skills. But even highly skilled people can make mistakes. Researchers have found that they can predict when a person will make a mistake 0.1 second before it happens. Now, they want to find out if they can increase that time up to 1 second-long enough to warn the person and prevent the mistake.

Objective:

To see if motor skill errors can be detected up to 1 second before they occur.

Eligibility:

Right-handed healthy adults aged 18 to 35.

Design:

Participants will have 2 to 5 study visits. Each visit will be 1 to 2 hours.

They will have a physical and neurological exam.

They will have 1 or 2 magnetic resonance imaging (MRI) scans. They will lie on a table that slides into a large cylinder. The MRI uses strong magnets to capture images of the inside of the body, including the brain.

They will have another scan, called magnetoencephalography (MEG). Small metal disks attached to wires will be taped to their head. Participants will sit in a padded chair with their head inside of a helmet. The helmet will not cover their eyes or face. Participants will perform a series of typing tasks on a keyboard. They will have short breaks between each round. Their head movements will be tracked, and their eye and finger movements will be videotaped.

Conditions

Healthy

Study ID

NCT06707207

Start date

Jun 17, 2026

Status verified date

Jul 7, 2026

Completion date

Oct 1, 2029

Anticipated

Primary completion date

Apr 1, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

  • INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Male or female, aged 18-35
  • In good general health as evidenced by medical history and normal neurological examination as determined by the screening clinician
  • English speaking
  • Right-handedness as reported by participant
  • Ability of subject to understand and the willingness to sign a written informed consent document

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

  • HCPS-affiliated NIH staff (i.e. - staff from our section)
  • Current pregnancy
  • Contraindications for MRI, or MEG
  • Severe or progressive neurological, psychological or medical condition as determined by the medical history review or physical and neurological exam.

Study Design

Enrollment

40 participants

Anticipated

Interventions and Outcome Measures

Arms

Healthy

Healthy young volunteers

Primary outcome measure

  • To detect future skill errors up to approximately 1 s before they occur [ Time Frame: 60 months ]

Central Contacts and Locations

Central contacts

Catherine L Blumhorst, C.R.N.P.

(301) 451-1335cathy.blumhorst@nih.gov

Leonardo G Cohen, M.D.

(301) 496-9782cohenl1@mail.nih.gov

Locations

National Institutes of Health Clinical Center

Recruiting

Bethesda, Maryland, United States, 20892

Contacts

NIH Clinical Center Office of Patient Recruitment (OPR)

800-411-1222ccopr@nih.gov

More Information

Sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Last update posted

Jul 9, 2026

Last verified

Jul 7, 2026

Keywords

  • Healthy
  • Brain
  • Motor Skill

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by National Institute of Neurological Disorders and Stroke (NINDS) on 2026-07-09.