Recruiting

TTE vs. TEE

Sponsor:

Sunnybrook Health Sciences Centre

Code:

NCT06715371

Conditions

Heart Chambers

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Transthoracic Echocardiography (TTE) and Transesophageal Echocardiography (TEE)

Study Details

Brief summary:

This study aims to compare two common ultrasound techniques used during heart surgery: transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE). TTE is performed by placing an ultrasound probe on the chest, while TEE involves inserting a probe into the esophagus, which provides closer and clearer images of the heart. Both methods are part of routine care for patients undergoing heart surgery.

The goal of this study is to assess how well the measurements from TTE and TEE agree in evaluating heart chamber dimensions during surgery and to investigate how factors such as anesthesia, breathing techniques affect these measurements.

This research involves 114 adult patients scheduled for heart surgery at Sunnybrook Health Sciences Centre. Participants will have TTE performed before and after surgery, and TEE will be conducted during surgery. All procedures are part of the usual standard of care.

By comparing these imaging techniques, the study seeks to provide more accurate and up-to-date guidelines for cardiac measurements, ensuring better care for patients during heart surgery.

Conditions

Heart Chambers

Study ID

NCT06715371

Start date

Jan 27, 2025

Status verified date

Nov, 2024

Completion date

Jun, 2026

Anticipated

Primary completion date

Mar 2, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥ 18, able to provide informed consent.
  • Patients scheduled for coronary revascularization cardiac surgery under general anesthesia.
  • With normal left ventricular (LV) systolic function, defined by an ejection fraction of 50% or more, and normal right ventricular (RV) systolic function.
  • Requiring intraoperative echocardiographic assessment.

Exclusion Criteria:

  • Patients with contraindications to either transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE).
  • History of poor-quality echocardiography data that preclude accurate assessment.
  • Undergoing emergency cardiac surgery.

Study Design

Enrollment

114 participants

Anticipated

Interventions and Outcome Measures

Arms

Cardiac Surgery Patients

Patients undergoing cardiac surgery (eg., coronary revascularization) at Sunnybrook Health Sciences Centre.

Interventions

Transthoracic Echocardiography (TTE) and Transesophageal Echocardiography (TEE)

Transthoracic echocardiography (TTE) is a non-invasive imaging technique performed by placing an ultrasound transducer on the chest to obtain detailed heart images. TTE is conducted preoperatively on awake patients within two weeks prior to cardiac surgery, following ASE chamber quantification guidelines.

Transesophageal echocardiography (TEE) is an invasive imaging technique where an ultrasound transducer is placed in the esophagus, providing closer and clearer images of the heart. TEE is performed intraoperatively under general anesthesia as part of routine care.

Primary outcome measure

  • Correlation between preoperative TTE and intraoperative TEE measurements [ Time Frame: Within 2 weeks prior to surgery and during surgery ]

Central Contacts and Locations

Central contacts

Jacobo Moreno Garijo, MD, PhD

416-480-4864jacobo.morenogarijo@sunnybrook.ca

Lilia Kaustov, PhD

416-480-6100lilia.kaustov@sunnybrook.ca

Locations

Sunnybrook Health Sciences Centre

Recruiting

Toronto, Ontario, Canada, M4N 3M5

Contacts

Lilia Kaustov, PhD

416-480-6100lilia.kaustov@sunnybrook.ca

More Information

Sponsor

Sunnybrook Health Sciences Centre

Last update posted

Jul 3, 2025

Last verified

Nov, 2024

Keywords

  • Cardiac Imaging
  • Cardiac Chamber Dimensions
  • General Anesthesia
  • Cardiac Surgery
  • Imaging Agreement
  • Diagnostic Accuracy
  • Perioperative Care
  • Echocardiography

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Sunnybrook Health Sciences Centre on 2025-07-03.