Recruiting

Observational Study

Sponsor:

Laval University

Code:

NCT06719258

Conditions

Humidifier Lung

Mechanical Fragility

Respiratory Complication

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MR850

FP950

Study Details

Brief summary:

When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management of respiratory secretions.

The study compare two heated humidifiers already used in ICU.

Data will be collected retrospectively from June 1, 2021.

Conditions

Humidifier Lung

Mechanical Fragility

Respiratory Complication

Study ID

NCT06719258

Start date

Sep 20, 2024

Status verified date

Aug, 2025

Completion date

Jul, 2026

Anticipated

Primary completion date

Dec, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ≥ 18 years old
  • Admitted to intensive care
  • Under invasive mechanical ventilation with the usual indications for the use of a heated humidifier (prolonged invasive mechanical ventilation and / or protective ventilation requiring high respiratory rates.

Exclusion Criteria:

  • Mechanical venitilation immediately after surgery (<24h)
  • Imminent extubation or planned intubation of very short duration (<24h)
  • Enrolled in the SAVE-ICU study in the group receiving volatile agents with the AnaConDa system.

Study Design

Enrollment

40 participants

Anticipated

Interventions and Outcome Measures

Arms

MR850

20 subjects on this heating humidifier (Fisher \& Paykel MR850).

FP950

20 subjects on this heating humidifier (Fisher \& Paykel FP950).

Interventions

MR850

This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.

FP950

This humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.

Primary outcome measure

  • Endotracheal tube occlusion requiring emergency tube change [ Time Frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred) ]
  • Bronchoscopy [ Time Frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred) ]
  • Tracheal saline instillations [ Time Frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred) ]
  • Thick secretions [ Time Frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred) ]
  • Change humidifier settings [ Time Frame: At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred) ]

Central Contacts and Locations

Central contacts

François Lellouche

418-656-8711francois.lellouche@criucpq.ulaval.ca

Pierre-Alexandre Bouchard

418-656-8711pierre-alexandre.bouchard@criucpq.ulaval.ca

Locations

Institut Universitaire de Cardiologie et de Pneumologie de Québec

Recruiting

Québec, Quebec, Canada, G1V4G5

Contacts

Francois Lellouche

418-656-8711francois.lellouche@criucpq.ulaval.ca

More Information

Sponsor

Laval University

Last update posted

Aug 28, 2025

Last verified

Aug, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Laval University on 2025-08-28.