Recruiting

Hemodynamic ABI

Sponsor:

University of Chicago

Code:

NCT06725108

Conditions

Traumatic Brain Injury (TBI)

Intracerebral Hemorrhage

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of this observational study is to explore the relationship of heart function with the course and outcomes after traumatic brain injuries and nontraumatic intracerebral hemorrhage. The goal is to explore association between routinely collected hemodynamic and brain monitoring data.

Participants already taking intervention A as part of their regular medical care and the investigators will follow up with participants 6 months after discharging the hospital.

Conditions

Traumatic Brain Injury (TBI)

Intracerebral Hemorrhage

Study ID

NCT06725108

Start date

Dec 6, 2024

Status verified date

Mar, 2026

Completion date

Dec 6, 2026

Anticipated

Primary completion date

Dec 6, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion:

Patients who are:

  • Admitted to the University of Chicago Medical Center Neurocritical Care Unit
  • Adults between 18 years and 80
  • Admitted with Traumatic brain injury blunt and penetrating or nontraumatic intracerebral hemorrhage
  • post-resuscitation Glasgow Coma Scale (GCS) <9

Exclusion:

Patients who were:

  • Pre-existing heart failure
  • Moribund or neurological exam suggesting imminent brain death (bilateral, fixed and dilated pupils) on admission
  • Major polytrauma or admitted to the surgical trauma critical care service
  • Prisoner

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • functional outcomes [ Time Frame: 180 days after discharging the hospital ]

Central Contacts and Locations

Central contacts

Farima Fakhri, MD

3126102482farima.fakhri@bsd.uchicago.edu

Locations

University of Chicago

Recruiting

Chicago, Illinois, United States, 60637

Contacts

Farima Fakhri, MD

7737021220farima.fakhri@bsd.uchicago.edu

More Information

Sponsor

University of Chicago

Last update posted

Mar 4, 2026

Last verified

Mar, 2026

Keywords

  • Hemodynamic
  • Acute brain injury
  • Monitoring

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Chicago on 2026-03-04.