Recruiting

DroperidolDroperidol and QTc Interval Changes in ED Patients

Sponsor:

CHRISTUS Health

Code:

NCT06726811

Conditions

Emergency Department Patient

QTc Intervals Changes

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Droperidol injection

Study Details

Brief summary:

Objectives To assess the association of low-dose Droperidol administration in the emergency department with changes in the QTc interval.

Hypothesis Our study is designed to test the null hypothesis that there will be no clinically significant change in QTc interval after administration of 2.5mg of IV Droperidol during an emergency department visit.

Conditions

Emergency Department Patient

QTc Intervals Changes

Study ID

NCT06726811

Start date

Oct 17, 2024

Status verified date

Dec, 2024

Completion date

Sep 30, 2026

Anticipated

Primary completion date

Sep 30, 2025

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

ED patients ages 18 years or older in a cardiovascular-monitored bed who have both an ECG and a 2.5 mg dose of IV droperidol ordered by their treating physician will be eligible for inclusion.

Exclusion Criteria:

Refusal to provide consent.
Administration of droperidol before the first ECG is performed.
Inability to complete the consent form and questionnaire due to clinical instability, severe pain, or disorientation as determined by a study physician.

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Interventions

Droperidol injection

2.5 mg

Primary outcome measure

ECG Evaluation [ Time Frame: 30 minutes after Droperidol is given. ]

Central Contacts and Locations

Central contacts

Aaron K Bartoe, DO, MS

(863) 532-8408 aaronkbartoe@gmail.com

Peter Richman, MD, MBA

prichmanmdmba@gmail.com

Locations

CHRISTUS Spohn Hospital Corpus Christi-Shoreline

Recruiting

Corpus Christi, Texas, United States, 78405

Contacts

Aaron Bartoe, DO, MS

(817) 999-8167 aaronkbartoe@gmail.com

Peter Richman, MD, MS

(817) 999-8167 prichmanmdmba@gmail.com

More Information

Sponsor

CHRISTUS Health

Last update posted

Dec 17, 2024

Last verified

Dec, 2024

Keywords

Droperidol
QTc Interval Changes
Emergency Department Patients

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-26. This information was provided to ClinicalTrials.gov by CHRISTUS Health on 2024-12-17. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.