Recruiting

Corticosteroid vs. Nerve Block

Sponsor:

University of Minnesota

Code:

NCT06735027

Conditions

Glenohumeral Arthritis

Rotator Cuff Arthropathy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

intraarticular corticosteroid injection (IACI)

suprascapular nerve block (SSNB)

Study Details

Brief summary:

The purpose of this study is to evaluate conservative pain relief measures for patients suffering from glenohumeral arthritis or rotator cuff arthropathy. Conservative management of osteoarthritis is often first line treatment, and while a corticosteroid injection is frequently used, suprascapular nerve blocks have not often been described as an analgesic option in this population.

Conditions

Glenohumeral Arthritis

Rotator Cuff Arthropathy

Study ID

NCT06735027

Start date

Jan 2, 2025

Status verified date

Jan, 2026

Completion date

Jan 2, 2027

Anticipated

Primary completion date

Jan 2, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • diagnosis of glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are being offered injection

Exclusion Criteria:

  • uncontrolled diabetes (patients will be excluded if no HbA1c within a year or if it is 8 or greater"
  • known allergy to steroid or anesthetic
  • pregnant women
  • prisoners
  • patients with diminished capacity to consent to participation
  • children under 18 years of age
  • non-English speakers

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: intraarticular methylprednisolone acetate injection (IACI)

Patients with glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are poor surgical candidates or who are not interested in pursuing surgery randomized to intraarticular corticosteroid injection (IACI).

experimental: suprascapular nerve block (SSNB) with bupivacaine and triamcinolone

Patients with glenohumeral osteoarthritis, rheumatoid arthritis, or rotator cuff arthropathy who are poor surgical candidates or who are not interested in pursuing surgery randomized to suprascapular nerve block (SSNB)

Interventions

intraarticular corticosteroid injection (IACI)

The patient will be in a seated position. Correct patient, laterality, and procedure will be performed during the timeout. Ultrasound guidance will be used to identify the glenohumeral joint. The injection site will then be disinfected with an alcohol wipe. A 21, 22, or 23-gauge needle (depending on provider preference) will be advanced into the glenohumeral joint under direct ultrasound visualization. After entry into the glenohumeral joint, a negative aspiration will be performed. At that time, up to 1 mL of 40mg/mL methylprednisolone acetate will be injected be injected into the joint space.

suprascapular nerve block (SSNB)

The patient will be in a seated position. Correct patient, laterality, and procedure will be performed during the timeout. Ultrasound guidance will be used to identify the suprascapular nerve in its path at the suprascapular notch. After disinfection of the injection site with alcohol, anatomic landmarks for SSNB as described by Dangoisse et al. \[10\] will be marked with a marking pen. Ultrasound will be utilized to guide the tip of a 21, 22, or 23 gauge (depending on provider preference) needle to the floor of the suprascapular fossa while avoiding neurovascular structures. At that time, a mixture of up to 10 mL of 0.5% bupivacaine and 20 mg triamcinolone will be slowly injected to fill the fascial contents of the suprascapular fossa under direct ultrasound guidance.

Primary outcome measure

  • change in visual analog scale (VAS) for pain [ Time Frame: preintervention, 24 hours, 3 days, 1 month, and 3 months postintervention ]
  • single assessment numerical evaluation (SANE) of the shoulder [ Time Frame: preintervention, 24 hours, 3 days, 1 month, and 3 months postintervention ]
  • Oxford shoulder score (OSS) [ Time Frame: preintervention, 24 hours, 3 days, 1 month, and 3 months postintervention ]
  • American shoulder and elbow surgeons (ASES) score [ Time Frame: preintervention, 24 hours, 3 days, 1 month, and 3 months postintervention ]

Central Contacts and Locations

Central contacts

Locations

University of Minnesota

Recruiting

Minneapolis, Minnesota, United States, 55414

More Information

Sponsor

University of Minnesota

Last update posted

Jan 8, 2026

Last verified

Jan, 2026

Keywords

  • osteoarthritis
  • glenohumeral arthritis
  • rotator cuff arthropathy
  • corticosteroid injection
  • suprascapular nerve block

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Minnesota on 2026-01-08.