Recruiting

Novel INPUT Tool

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06743308

Conditions

Lung Carcinoma

Metastatic Lung Carcinoma

Stage IV Lung Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Best Practice

Questionnaire Administration

Study Details

Brief summary:

This clinical trial compares the use of a new screening tool designed to evaluate patients' information needs, preferences, and illness understanding to the usual care to improve illness understanding in patients with lung cancer that has spread from where it first started (primary site) to other places in the body (metastatic) or for which no curative treatment is currently available (incurable). Goal concordant care is a model of care that aligns a patient's medical care with their values, preferences, and goals. Often, patients may not fully understand their illness and prognosis, but this information is important so that they can make fully informed decisions regarding their care that are consistent with their values, preferences, and goals. Completing the Information Needs, Preferences, and Understanding Trial (INPUT) screening tool may allow for more frequent and regular discussions regarding disease status and treatment goals, ultimately resulting in improved patient illness understanding and goal concordant care for patients with metastatic or incurable lung cancer.

Conditions

Lung Carcinoma

Metastatic Lung Carcinoma

Stage IV Lung Cancer AJCC v8

Study ID

NCT06743308

Start date

Dec 16, 2024

Status verified date

Apr, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Within 3 months of biopsy-confirmed diagnosis of stage IV lung cancer
  • Age 18 or over
  • English speaking
  • Attending a follow-up visit at the thoracic medical oncology clinic
  • Plans to receive or actively undergoing cancer-directed systemic treatment at MD Anderson

Exclusion Criteria:

• Diagnosis of cognitive impairment or dementia requiring a surrogate decision maker

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

active comparator: Arm I (Standard care)

Patients undergo standard of care oncology follow-up visits.

experimental: Arm II (INPUT screening)

Patients complete the INPUT screening tool at each of their standard of care follow up visits, with their medical oncology team.

Interventions

Best Practice

Other Best Practice best practice, standard of care, standard of care, standard of care, standard therapy Undergo standard of care oncology follow-up visits

Questionnaire Administration

Ancillary studies

Primary outcome measure

  • Change in illness understanding [ Time Frame: At 3 months ]

Central Contacts and Locations

Central contacts

Kayley M Ancy, MD

832-729-1621kmclemings@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Kayley M Ancy, MD

832-729-1621kmclemings@mdanderson.org

Principal Investigator:

Kayley M Ancy, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Apr 29, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-04-29.