Recruiting

Mango Consumption

Sponsor:

San Diego State University

Code:

NCT06800833

Conditions

Gut Microbiome

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Interventions

Low fat cookies

Mango

Study Details

Brief summary:

The objective of the proposed research is to determine the effects of fresh mango consumption on gut microbiome, and its relationship with skin health, sexual and mental health in relatively healthy adults.

Conditions

Gut Microbiome

Study ID

NCT06800833

Start date

Jan 23, 2025

Status verified date

Jan, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Generally healthy subjects
  • BMI 20-40 kg/m2

Exclusion Criteria:

  • Smoker
  • Pregnant woman
  • Required antibiotics use
  • Required dietary supplement use
  • Required medication of metabolic disorders, mental health and sexual health
  • Allergy to mango or wheat

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: Low fat cookies

Subjects consume 100 kcal of low-fat cookies daily for 4 weeks.

experimental: Mango

Subjects consume 100 kcal of mango daily for 4 weeks.

Interventions

Low fat cookies

To determine the effects of low fat cookie consumption on physiological indicators of sexual, mental, skin, and gut health

Mango

To determine the effects of mango consumption on physiological indicators of sexual, mental, skin, and gut health

Primary outcome measure

  • Change of sexual health questionnaire scores [ Time Frame: Baseline and week 4 ]
  • Change of depression questionnaire scores [ Time Frame: Baseline and week 4 ]
  • Change of skin hydration scores [ Time Frame: Baseline, 1 min post application and week 4consumption ]
  • Change of microbiome diversity [ Time Frame: Baseline and week 4 ]

Central Contacts and Locations

Locations

San Diego State University

Recruiting

San Diego, California, United States, 92182

Contacts

Mee Young Hong

619-594-6825mhong2@sdsu.edu

More Information

Sponsor

San Diego State University

Last update posted

Jan 30, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by San Diego State University on 2026-01-30.