Recruiting

Observational Study

Sponsor:

Brown University

Code:

NCT06822569

Conditions

Health Behavior

Wellness, Psychological

Substance Use

Eligibility Criteria

Sex: All

Age: 13 - 16

Healthy Volunteers: Accepted

Interventions

Cue reactivity paradigm

Study Details

Brief summary:

The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older. Participants, ages 13 to 16, will be asked to use a smartphone application developed for this research study. Participants will also come to Brown University or meet via video conference to answer questions about specific behaviors, choices, and feelings that may change over time.

Conditions

Health Behavior

Wellness, Psychological

Substance Use

Study ID

NCT06822569

Start date

Dec 27, 2024

Status verified date

Mar, 2025

Completion date

Feb, 2028

Anticipated

Primary completion date

Feb, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 13 - 16

Healthy Volunteers: Accepted

Inclusion Criteria:

1. be age 13 to 16 years
2. engage in a target health behavior on at least one recent occasion
3. speak, read, and understand English or Spanish
4. live in or near Rhode Island

Exclusion Criteria:

1. lifetime history of moderate or severe substance use disorder or treatment, excluding nicotine use disorder
2. current psychotic symptoms or active suicidality (i.e., intent in the past 30 days)

Study Design

Enrollment

224 participants

Anticipated

Intervention Model

Single group

Primary purpose

Screening

Interventions and Outcome Measures

Arms

other: Naturalistic, longitudinal

Teenagers ages 13 to 16 years at the time of recruitment.

Interventions

Cue reactivity paradigm

Participants will be exposed to cues in a fixed sequence while they answer questions about their emotions and thoughts. The cues will include everyday items (e.g., an ink pen) and substance-related items (e.g., a vape pen).

Primary outcome measure

  • Maximum subjective craving during cannabis cue exposure (rated on a 0 to 10 scale). [ Time Frame: Baseline, 1 year, 2 years ]

Central Contacts and Locations

Central contacts

Primary Researcher

401-863-6623teenhealth@brown.edu

Locations

Brown University School of Public Health

Recruiting

Providence, Rhode Island, United States, 02903

Contacts

Primary Researcher

401-863-6623teenhealth@brown.edu

Project Coordinator

401-863-6670teenhealth@brown.edu

Principal Investigator:

Hayley T Padovano, PhD

More Information

Sponsor

Brown University

Last update posted

Apr 2, 2025

Last verified

Mar, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-21. This information was provided to ClinicalTrials.gov by Brown University on 2025-04-02.