Recruiting

Observational Study

Sponsor:

HeartFlow, Inc.

Code:

NCT06831409

Conditions

Coronary Artery Disease (CAD)

Heart Disease

Coronary Atherosclerosis

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Coronary computed tomography angiography

Study Details

Brief summary:

The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the presence of CAD in NFL alumni.

Conditions

Coronary Artery Disease (CAD)

Heart Disease

Coronary Atherosclerosis

Study ID

NCT06831409

Start date

Dec 17, 2024

Status verified date

Aug, 2025

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Retired NFL player

Exclusion Criteria:

  • CCTA not successfully processed for FFRct and AI-Plaque

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Arms

NFL Alumni

A retired NFL player is defined as any former player who made either a practice squad or an active NFL roster.

Interventions

Coronary computed tomography angiography

Coronary Computed Tomography Angiography (CCTA) is a non-invasive medical imaging test that uses X-rays to create detailed 3D images of the heart and its blood vessels, specifically the coronary arteries.

Primary outcome measure

  • Participants with CAD [ Time Frame: 24 hours from the time CCTA was taken ]

Central Contacts and Locations

Central contacts

HeartFlow

650-241-1221GAMEFILM@heartflow.com

Locations

Boone Heart Institute

Recruiting

Greenwood Village, Colorado, United States, 80111

More Information

Sponsor

HeartFlow, Inc.

Last update posted

Aug 26, 2025

Last verified

Aug, 2025

Keywords

  • NFL
  • Heart Disease

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-26. This information was provided to ClinicalTrials.gov by HeartFlow, Inc. on 2025-08-26. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.