Recruiting

Smoking Cessation

Sponsor:

University of Chicago

Code:

NCT06837220

Conditions

Nicotine Use Disorder

Smoking Cessation

Smoking Cessation Intervention

Eligibility Criteria

Sex: All

Age: 18 - 26

Healthy Volunteers: Not accepted

Interventions

Enhanced Courage to Quit

Study Details

Brief summary:

The goal of this study is to: partner with Respiratory Health Association and determine barriers and unmet smoking cessation treatment needs from leaders in behavioral health organizations, treatment programs and adults who smoke (AWS) in Chicago. This will be accomplished by establishing a community advisory board (CAB) and pilot testing a community-informed smoking cessation treatment within a community behavioral health organization to determine its feasibility after addressing implementation issues.

Conditions

Nicotine Use Disorder

Smoking Cessation

Smoking Cessation Intervention

Study ID

NCT06837220

Start date

Jul 20, 2026

Status verified date

Jul, 2026

Completion date

May, 2027

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 26

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Identify as someone who currently smokes combustible cigarettes (at least 1 cigarette per day) on each day for the past month
  • Report interest in quitting cigarettes (at least 6/10 scale in interest of quitting)
  • Age 18 or older, ability to understand the English language, willing and able to provide informed consent
  • Stable residence and contact information throughout the follow up period

Exclusion Criteria:

  • Non-daily or intermittent cigarette use
  • No interest in quitting smoking
  • Unstable residence/not staying in Chicago for duration of study period
  • Current untreated severe substance use disorder (with the exception of tobacco use) or past-year serious untreated psychiatric illness (e.g. schizophrenia, bipolar disorder, obsessive compulsive disorder, unspecified psychosis, past-year suicide attempt)

Study Design

Enrollment

24 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Pilot Intervention

The participants in this arm will take part in a pilot test of a community-targeted smoking cessation treatment. This treatment will be evidence-based smoking treatment using cognitive behavioral and motivational strategies implemented according to findings from Phase 1 of this study. The original intervention has four core sessions that will be modified accordingly to fit community needs. Participants will complete pre- and post-session questionnaires regarding their smoking status, quit attempts, use of smoking cessation aids, and other surveys.

Interventions

Enhanced Courage to Quit

Participants will engage in a version of the smoking cessation treatment "Courage to Quit" that has been optimized for implementation in community behavioral health clinics. The group will run over a period of 3 months, where participants will learn behavioral and cognitive skills for smoking cessation and/or reduction. Special attention will be given to the unique needs of the community, such as technology options or more flexible treatment models. The goal of this intervention is to prove that it is feasible to implement, and can create enhanced engagement and smoking outcomes for adults who smoke (AWS) and have fewer socioeconomic resources.

Primary outcome measure

  • Number of participants who attend the enhanced intervention as assessed by enrollment and sign-in at each session [ Time Frame: 3 months ]
  • Feasibility will be assessed by calculating the portion of people who enroll (attend at least on session) and complete 4+ sessions versus those who drop out before finishing 4 sessions as assessed by session sign-in [ Time Frame: 3 months ]
  • A modified version of the Client Satisfaction Questionnaire (CSQ) will assess intervention acceptability. [ Time Frame: End of treatment (e.g., 3 months or fourth session attended, whichever comes first) ]

Central Contacts and Locations

Central contacts

Emma Brett, PhD

773-834-5341ebrett@bsd.uchicago.edu

Sophie Miller, BS

sophie.miller@bsd.uchicago.edu

Locations

The University of Chicago

Recruiting

Chicago, Illinois, United States, 60637

Contacts

Emma I. Brett, PhD

773-834-5341ebrett@bsd.uchicago.edu

Sophie R Miller, B.S.

7738089807sophie.miller@bsd.uchicago.edu

Principal Investigator:

Emma I Brett, PhD

More Information

Sponsor

University of Chicago

Last update posted

Jul 7, 2026

Last verified

Jul, 2026

Keywords

  • smoking
  • smoking cessation
  • nicotine
  • nicotine use disorder
  • quitting smoking
  • quitting nicotine
  • respiratory health
  • telehealth
  • virtual
  • tobacco
  • tobacco treatment
  • community
  • behavioral health
  • chicago
  • group therapy
  • disparities
  • adults who smoke
  • cigarettes
  • tobacco cessation
  • cessation
  • abstinence
  • substance use
  • substance abuse
  • addiction
  • counseling
  • health counseling
  • health communication

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by University of Chicago on 2026-07-07.