Recruiting

HIV Service Engagement

Sponsor:

San Diego State University

Code:

NCT06848686

Conditions

HIV

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Prevention Ambassadors

SSP Standard of Care

Study Details

Brief summary:

HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the SSP-based "Prevention Ambassadors" (PA) intervention to promote HIV testing and service uptake among PWUD via the secondary distribution (i.e., peer delivery) of HIV self-testing (HIVST) kits with local HIV service information and referrals to HIV service navigation in the social networks of SSP clients (i.e., PWUD). The PA intervention will then be piloted to assess its preliminary effects, acceptability, and feasibility among PWUD in the Ending the HIV Epidemic priority jurisdiction of Riverside County, California.

Conditions

HIV

Study ID

NCT06848686

Start date

Feb 3, 2025

Status verified date

Jan, 2026

Completion date

Feb, 2027

Anticipated

Primary completion date

Jul, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Index Participant Inclusion Criteria:

  • Being greater than or equal to 18 years old
  • Reporting drug use (past month)
  • Having other people who use drugs (PWUD) in one's social network
  • Being willing to talk about HIV testing and services with at least 2 PWUD in their networks and attempt to refer them to the study
  • Speaking English fluently

Peer-Recruit Participant Inclusion Criteria:

  • Being greater than or equal to 18 years old
  • Reporting drug use (past 3 months)
  • Being recruited by an index participant (evidenced by presenting the coupon used to recruit them)
  • Speaking English fluently

Exclusion Criteria:

\- Persons who participated in formative study activities related to the development of the PA intervention will not be eligible to participate.

Study Design

Enrollment

210 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Prevention Ambassadors

other: SSP Standard of Care

Interventions

Prevention Ambassadors

Delivery of prevention supplies and information on local services plus training to build the capacity of PWUD to distribute HIV self-testing (HIVST) kits with information and referrals to other PWUD in their social networks to promote HIV testing and HIV service engagement among PWUD.

SSP Standard of Care

Delivery of prevention supplies and information on local services.

Primary outcome measure

  • HIV testing (past 3 months) [ Time Frame: 3-month follow-up ]
  • Linkage to PrEP/HIV care (past 3 months) [ Time Frame: 3-month follow-up ]
  • PrEP/ART uptake (past 3 months) [ Time Frame: 3-month follow-up ]

Central Contacts and Locations

Central contacts

Heather Pines

619-594-2481hpines@sdsu.edu

Locations

San Diego State University

Recruiting

San Diego, California, United States, 92182

Contacts

Heather Pines

619-594-2481hpines@sdsu.edu

More Information

Sponsor

San Diego State University

Last update posted

Jan 29, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by San Diego State University on 2026-01-29.