Recruiting

Glaucoma Screening

Sponsor:

UCLA

Code:

NCT06854198

Conditions

Glaucoma

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Interventions

Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometry

Educational Brochure

Study Details

Brief summary:

The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and may be amenable to screening through telemedicine-based approaches. This study is a randomized trial to evaluate whether glaucoma screening with established tests (e.g., optical coherence tomography, fundus photography, and tonometry) is more effective for detecting undiagnosed glaucoma cases compared to education alone or delayed intervention.

Conditions

Glaucoma

Study ID

NCT06854198

Start date

Feb 10, 2026

Status verified date

Apr, 2026

Completion date

Sep, 2029

Anticipated

Primary completion date

Mar, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Black people aged 50 years or older
  • Hispanic people aged 65 years or older
  • People with diabetes aged 50 years or older
  • Must have been seen at the Federally Qualified Health Center (FQHC) within the past month

Exclusion Criteria:

  • Patients without a valid phone number or mailing address
  • Patients who have had an optometry appointment within the past year

Study Design

Enrollment

2000 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Screening

active comparator: Education

no intervention: Delayed Education

The same as the Educational Brochure arm, but delivered at the conclusion of the study.

Interventions

Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometry

Participants will be called and offered a screening appointment. At the appointment, visual acuity, OCT, color fundus photography, tonometry, and visual field testing will be performed. The images will be assessed for abnormalities. Participants meeting referral criteria will be referred for a comprehensive eye examination with an eye care provider.

Educational Brochure

A brochure about glaucoma screening will be mailed to participants. The brochure will include contact information of a staff member who can schedule an appointment for a comprehensive eye examination.

Primary outcome measure

  • Glaucoma Diagnosis or Glaucoma Suspect Requiring Treatment [ Time Frame: 3 months from randomization ]

Central Contacts and Locations

Central contacts

Atnasia Mekonnen, MS

510-603-3330atnasia.mekonnen@ucsf.edu

Dionna Wittberg, MPH

330-308-3016dionna.wittberg@ucsf.edu

Locations

Baywell Health

Recruiting

Oakland, California, United States, 94607

Contacts

Angela Shahbazian, OD, FAAO

(510) 835-9610a.shahbazian@berkeley.edu

More Information

Sponsor

University of California, San Francisco

Last update posted

Apr 15, 2026

Last verified

Apr, 2026

Keywords

  • optical coherence tomography
  • tonometry
  • glaucoma
  • screening

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-04-15.