Recruiting

Hepatitis C

Sponsor:

University of Southern California

Code:

NCT06870019

Conditions

Hepatitis C Virus Infection

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

GPS tracker device

Study Details

Brief summary:

The goal of this study is to determine if GPS tracking can enhance adherence to hepatitis C treatment among patients diagnosed with hepatitis C infection who are also experiencing unsheltered homelessness and receiving street medicine. Research will compare medication adherence among participants randomly assigned to receive standard medical care for Hepatitis C versus the standard medical care for Hepatitis C along with GPS tracking assistance.

Conditions

Hepatitis C Virus Infection

Study ID

NCT06870019

Start date

Aug 8, 2025

Status verified date

Aug, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosed with Hepatitis C infection
  • Experiencing unsheltered homelessness at study initiation
  • Speaks English or Spanish
  • Receiving street medicine care
  • Meet the American Association for the Study of Liver Diseases (AASLD) criteria for simplified treatment of Hepatitis C

Exclusion Criteria:

  • Prior engagement in HCV treatment
  • Decompensated cirrhosis; HBsAg positive
  • Current pregnancy; Known or suspended hepatocellular carcinoma
  • Prior liver transplantation

Study Design

Enrollment

124 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

no intervention: Standard HCV treatment

Participants randomized to this study arm will receive the standard medical care for Hepatitis C.

active comparator: Standard HCV treatment + GPS tracker device

Participants randomized to this study arm will receive the standard medical care for Hepatitis C and a GPS tracker device.

Interventions

GPS tracker device

GPS tracker device

Primary outcome measure

  • Medication Adherence Rate [ Time Frame: 8-12 weeks ]
  • Length of treatment course [ Time Frame: 8-12 weeks ]

Central Contacts and Locations

Central contacts

Alexis Coulourides Kogan, PhD

626-457-4207acoulour@usc.edu

Locations

USC Street Medicine

Recruiting

Alhambra, California, United States, 91803

Contacts

Alexis Coulourides Kogan, PhD

626-457-4204acoulour@usc.edu

Principal Investigator:

Camilo Zaks, MD

Ventura County Medical Center

Recruiting

Ventura, California, United States, 93003

Contacts

Matthew Lamon, DO

805-652-6100Matthew.Lamon@ventura.org

Principal Investigator:

Tipu Kahn, MD

More Information

Sponsor

University of Southern California

Last update posted

Aug 29, 2025

Last verified

Aug, 2025

Keywords

  • Street medicine
  • Unsheltered homelessness
  • Hepatitis C
  • GPS tracker
  • Mixed-methods
  • Ill-housed person

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Southern California on 2025-08-29.