Recruiting

Observational Study

Sponsor:

Stanford University

Code:

NCT06880341

Conditions

Moya Moya Disease

Eligibility Criteria

Sex: All

Age: 3+

Healthy Volunteers: Not accepted

Interventions

Standard of Care

Study Details

Brief summary:

The goal of this study is to study the incidence of post-operative Transient Neurologic Events (TNEs) within 30 days postoperatively, as assessed by clinical neurological scales, binned by week. Collect data on all interventions and assessments performed during the recovery post surgery up to 30 days, to understand what factors might cause Transient Neurologic Events (TNEs) and determine how these can be reduced in Moyamoya subjects post surgery.

Conditions

Moya Moya Disease

Study ID

NCT06880341

Start date

May 21, 2025

Status verified date

May, 2025

Completion date

Mar 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 3+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Moyamoya Disease (MMD) patients undergoing direct extracranial-intracranial (ECIC) bypass. Patients above the age of 3 years old are eligible for the study

Exclusion Criteria:

  • Renal dysfunction, electrolyte disturbances neuromuscular disorders including Myaesthenia Gravis, heart block

Study Design

Enrollment

88 participants

Anticipated

Interventions and Outcome Measures

Arms

MoyaMoya Subjects

Subjects will receive standard of care moyamoya surgical intervention and be followed for 30 days post for transient neurological episodes (TNEs).

Interventions

Standard of Care

Standard of care treatment of Transient Neurologic Events (TNEs) as needed

Primary outcome measure

  • Transient Neurologic Events (TNEs) [ Time Frame: 30 days post-surgery ]

Central Contacts and Locations

Central contacts

Jinendra Ekanayake

650-660-1266jine7000@stanford.edu

Anthony Bet

abet0915@stanford.edu

Locations

Stanford University Hospital

Recruiting

Palo Alto, California, United States, 94305

Contacts

Gabriella Morton, BS

6503047766neurosurgeryresearch@stanford.edu

Sasha Alexander

neurosurgeryresearch@stanford.edu

More Information

Sponsor

Stanford University

Last update posted

May 28, 2025

Last verified

May, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2025-05-28.