Recruiting

Cystectomy Comparison

Sponsor:

Mayo Clinic

Code:

NCT06891209

Conditions

Bladder Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This study explores and compares health-related quality of life and urinary outcomes in postoperative partial cystectomy and matched radical cystectomy patients.

Conditions

Bladder Carcinoma

Study ID

NCT06891209

Start date

Jan 15, 2025

Status verified date

Aug, 2026

Completion date

Jan 31, 2027

Anticipated

Primary completion date

Jan 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Currently living partial cystectomy patients in Mayo Urology's cystectomy registry and patients undergoing radical or partial cystectomy
  • Matched 2:1 living radical cystectomy to partial cystectomy patients
  • Either urothelial or non-urothelial histology

Exclusion Criteria:

  • Partial cystectomy patients that underwent subsequent radical cystectomy

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational - Radical Cystectomy

Patients complete questionnaires and have their medical records reviewed on study.

Observational - Partial Cystectomy

Patients complete questionnaires and have their medical records reviewed on study.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

  • Health-related quality of life - EORTC QLQ-C30 [ Time Frame: Up to 1 year ]
  • Self-reported urinary outcomes [ Time Frame: Up to 1 year ]

Central Contacts and Locations

Central contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Locations

Mayo Clinic in Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Gianni Morales Martinez

507-538-1447moralesmartnez.gianni@mayo.edu

Principal Investigator:

Vidit Sharma, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Aug 11, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-08-11.