Recruiting

Massage

Sponsor:

Children's Hospital of Philadelphia

Code:

NCT06892158

Conditions

Cancer

Pediatric Cancer

Chemotherapy Effect

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia, Pediatric

Eligibility Criteria

Sex: All

Age: 12 - 21

Healthy Volunteers: Not accepted

Interventions

Massage therapy

Standard of care

Study Details

Brief summary:

This study aims to determine the impact of massage therapy for pediatric patients receiving intensive chemotherapy or stem cell transplant (SCT).

Conditions

Cancer

Pediatric Cancer

Chemotherapy Effect

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia, Pediatric

Study ID

NCT06892158

Start date

Jan 23, 2025

Status verified date

Apr, 2026

Completion date

Jul, 2028

Anticipated

Primary completion date

Jan, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12 - 21

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Diagnosis of cancer, such as acute myeloid leukemia (AML) or relapsed acute lymphoblastic leukemia (rALL) OR admitted to receive autologous or allogeneic HSCT for any indication
2. Expected to be an inpatient for at least 21 days
3. Aged 12 to 21 years at enrollment.
4. Inpatient at Children's National or Children's Hospital of Philadelphia (CHOP).

Exclusion Criteria:

1. Cognitive impairment sufficient to preclude completing questionnaires appropriately
2. Insufficient knowledge of English or Spanish that would prohibit completing the study instruments
3. Previous enrollment

Study Design

Enrollment

70 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Control Arm (CA)

Standard of care.

experimental: Intervention Arm (IA)

Massage therapy

Interventions

Massage therapy

Participants in IA will receive a 20-30-minute massage five days per week for 21 days.

Standard of care

Institutional standard of care treatment

Primary outcome measure

  • Change in total sleep minutes [ Time Frame: 3 weeks ]

Central Contacts and Locations

Central contacts

Lauren Vernau

267-426-1162vernaul@chop.edu

Locations

Children's Hospital of Philadelphia

Recruiting

Philadelphia, Pennsylvania, United States, 19104

Contacts

Tracey Jubelirer, MD

jubelirer@chop.edu

Lauren Vernau

vernaul@chop.edu

More Information

Sponsor

Children's Hospital of Philadelphia

Last update posted

Apr 15, 2026

Last verified

Apr, 2026

Keywords

  • Stem cell transplant (SCT)
  • Decreased sleep efficiency
  • Pediatric cancer diagnosis
  • Circadian activity rhythm (CAR)

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Children's Hospital of Philadelphia on 2026-04-15.