Recruiting

TMS

Sponsor:

University of Calgary

Code:

NCT06892847

Conditions

Anxiety Disorders

Depression

Eligibility Criteria

Sex: All

Age: 6 - 18

Healthy Volunteers: Not accepted

Interventions

Transcranial Magnetic Stimulation

Study Details

Brief summary:

In this open-label trial, the overall aim is to determine if TMS treatment can improve anxiety and depression in a broad group of children and youth referred by physicians.

Conditions

Anxiety Disorders

Depression

Study ID

NCT06892847

Start date

Jul 1, 2025

Status verified date

Jan, 2026

Completion date

Dec 31, 2028

Anticipated

Primary completion date

Dec 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 6 - 18

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. aged between 6 and 18 years old
2. diagnosis of anxiety or depression made by a qualified medical professional
3. active anxiety and/or depression symptoms

Exclusion Criteria:

1. status epilepticus in past 12-months
2. presence of any disease, medical condition, or physical condition that, in the opinion of the study investigator may compromise, interfere, limit, affect, or reduce the participant's ability to complete the study
3. hospitalization for suicide attempt within the past 3 months (unless participant is under the daily supervision of a physician, such as in a mental health day treatment program)
4. TMS-related contraindications, including implanted medical devices (e.g., pacemaker)
5. if actively taking prescription medication, no changes in medication for at least 3 months prior to entry into the study, with no anticipation of change in the frequency or dose over the duration of the study, unless changes to medication are required for participant safety
6. unable to understand instructions in English

Study Design

Enrollment

120 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Transcranial Magnetic Stimulation (TMS)

Open-label study with active TMS for treatment.

Interventions

Transcranial Magnetic Stimulation

Participants will receive TMS for treatment measures as determined by referral and presentation.

Primary outcome measure

  • Revised Children Anxiety and Depression Scale (RCADS) [ Time Frame: Baseline and 5 weeks. ]

Central Contacts and Locations

Central contacts

Locations

Alberta Children's Hospital

Recruiting

Calgary, Alberta, Canada, T3B 6A8

Contacts

More Information

Sponsor

University of Calgary

Last update posted

Jan 29, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Calgary on 2026-01-29.