Recruiting

Pink & Pearl Campaign

Sponsor:

Washington University School of Medicine

Code:

NCT06898333

Conditions

Lung Cancer

Cancer of the Lung

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The investigators proposal is ripe for executing as the investigators seek to leverage this "natural experiment" initiated by the BJC health system to evaluate the effectiveness of the Pink \& Pearl Campaign as an implementation strategy to promote lung cancer screening (LCS) uptake among LCS-eligible women undergoing mammography at BJC West County. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, the research questions and specific aims for this proposal are to: a) evaluate the baseline prevalence of LCS among LCS-eligible women; b) assess whether the Pink \& Pearl Campaign increases referrals and uptake/ completion of LCS among LCS-eligible women undergoing screening mammography; and c) evaluate individual and environmental factors influencing LCS uptake, and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Conditions

Lung Cancer

Cancer of the Lung

Study ID

NCT06898333

Start date

May 8, 2025

Status verified date

Aug, 2026

Completion date

May 31, 2027

Anticipated

Primary completion date

Nov 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria for Participants:

  • Undergoing screening mammography
  • Between the ages of 50-80 years (inclusive)
  • Reporting a 20 pack-year equivalent of either current smoking history or have quit in the past 15 years
  • Can speak and understand English
  • Ability to understand willingness to provide informed consent.

Exclusion Criteria for Participants:

  • Diagnosed with a serious health problem that will likely limit life expectancy (such as previous history of lung cancer, symptoms of lung cancer such as hemoptysis or unexplained weight loss of more than 6.8 kg (15 lb) in the previous year)

  • Subjects with symptoms of lung cancer should get a diagnostic CT scan
  • Unable or unwilling to get treatment if lung cancer is found

Eligibility Criteria for Providers:

  • Older than 20 years of age

Study Design

Enrollment

279 participants

Anticipated

Interventions and Outcome Measures

Arms

Participants - scheduled for mammography and eligible for LCS

Women who are scheduled for mammography and are potentially LCS-eligible will be approached by the registration team and will complete a survey. Subjects who were referred for LCS will be contacted and the investigators will gauge their interest in returning for dual breast and lung screening program in future and rate their experience on a patient satisfaction scale.

Providers

Providers in the breast radiology service who referred women to LCS. Investigators will gather information on the feasibility, acceptability, and appropriateness of the Pink and Pearl project.

Primary outcome measure

  • Prevalence of LCS-eligible women who opt-in to, and successfully, complete LCS mammography and opt-in to lung cancer screening [ Time Frame: At baseline ]
  • Number of women screened for LCS [ Time Frame: At 3 months ]
  • Number of women screened for LCS [ Time Frame: At 6 months ]
  • Feasibility of Pink and Pearl project [ Time Frame: At 6 months ]
  • Acceptability of Pink and Pearl project [ Time Frame: At 6 months ]
  • Appropriateness of Pink and Pearl project [ Time Frame: At 6 months ]

Central Contacts and Locations

Central contacts

Beryne Odeny, M.D., MPH, Ph.D.

314-362-1183beryne@wustl.edu

Locations

Barnes-Jewish Hospital West County

Recruiting

Creve Coeur, Missouri, United States, 63141

Contacts

Beryne Odeny, M.D, MPH, Ph.D.

314-362-1183beryne@wustl.edu

Principal Investigator:

Beryne Odeny, M.D., MPH, Ph.D.

More Information

Sponsor

Washington University School of Medicine

Last update posted

Aug 12, 2026

Last verified

Aug, 2026

Keywords

  • Lung cancer screening (LCS)
  • Pink and Pearl Campaign
  • Breast cancer screening (BCS)
  • Low-dose computed tomography (LDCT)
  • Smoking history
  • Health disparities
  • Screening behavior
  • Feasibility
  • Acceptability
  • Appropriateness

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2026-08-12.